The one on the top of my mind is MESCALINE. Some people cannot take mescaline without getting nausea. An enteric coated capsule of mescaline will solve the problem. Also some drugs are actually destroyed by the acid in the stomach, and rendered inactive, so an enteric coating is needed for them.

Enteric coatings can also prevent resalting of drugs. Some drugs have better action as certains salts, or even as freebase. But when they enter the stomach, the stomach acid can make them into hydrochlorides. For example, some mescaline acetate that enters the stomach is converted to mescaline HCl, especially if it sits in the stomach too long. Freebase DMT can become DMT Hcl.

I think bufotenine would also be a good candidate for this. Freebase bufotenine cannot be used orally because it becomes the unpleasant bufotenine HCl. Putting freebase bufotenine in an enteric coated capsule would prevent that. So it might be possible to experience a freebase bufotenine trip orally if one used an enteric coated capsule.

There are many uses for this.

SWIM wants to try freebase bufotenine orally in an enteric coated capsule. I believe that would produce a trip nearly equal to smoking it without all the unpleasantness of oral bufotenine taken without an enteric coating.