I read a while ago that 69ron claimed taking 2 datura seeds, and also as his "swim" anecdotally preferred varieties with more hyoscyamine content to reduce nausea and supposedly "potentiate" visuals with most psychedelics and also claimed his experiences to be more "LSD" like. I do not believe any 2 cents of this. How? I ate 2 Datura metel seeds I had laying around which I believe are very up there with its hyoscyamine way more so than its scopolamine content, then ate 2.5 g of Blue Meanies after in attempt just to maybe try to reduce nausea more than anything, and I'll tell you this, it was almost nothing at all close to what I could ever hear from quite a distance to anything close to any pscyhedelic, no, no. This just poisoned everything, instead of the euphoria with the clean headspace and smooth body load with the bright and curvy flowing visuals I usually feel with psilocybin, this just made it feel like straight up searing utter torture both physically and mentally. It has been 3 weeks almost since I have taken any hallucinogens and am skittishly terrified and panicked of how to clear this, let me know if anyone has any good ideas on how to reverse this muscarinic choline receptors antagonism from out of its core without having to go to a hospital to be injected physostigmine, is there anything naturally that may possibly reverse this, I tried to be very careful and ultimately regret making this terrible choice. I do not want to be stuck with this, please I need some help to prevent myself from causing any further damage ASAP!
-
Members of the previous forum can retrieve their temporary password here, (login and check your PM).
Accidental threshold/theraputic dose of datura metel in attempt to reduce nausea from psilocybin gone terribly wrong, need a way to reverse antagonism
- Thread starter alank
- Start date
Sorry to hear that you may have fallen foul of some possible 69ron misinformation.
That being said, atropine and scopolamine won't have any action lasting over two weeks, so physostigmine probably won't help at this stage. D. metel seeds contain 0.2 - 0.5% alkaloids; you'd have to know the weight of the seeds to estimate the dose you took.
The tropane alkaloids may have contributed to a bad trip, but now you're dealing with the trauma of that. Concentrate on eating good, simple food, getting some exercise and fresh air - preferably out in nature - and developing a healthy sleep routine. Calming herb teas like lemon balm, chamomile, lavender and skullcap may also be a useful addition at this stage.
If your mental or physical discomfort continues to feel unbearable I would strongly advise you to consult a physician. We are not able to give medical advice at the Nexus, apart perhaps from one or two members who are actual physicians.
If you feel like talking to people some more, consider visiting our chat room.
Datura metel ime is a scopolamine dominant species, and regardless of that, I don't prefer it. İt's seeds are also quite large, so 2 seeds most likely would be a strong dose and not a subtle tweak.
2-3 Datura stramonium seeds together with my Ayahuasca analogue felt healthy and enhancing the experience/healing in my brief time of experimentation almost 2 years ago. This species is hyoscyamine dominant for sure.
İf your quest is only to reduce nausea, then there should be much less complicated or risky plants that can do the job. Datura will bring much more than reducing nausea.
As transform says, you need energetic healing at this point. Sleep well, ground yourself on the earth, eat healthy. Do things that heal you in general.
2-3 Datura stramonium seeds together with my Ayahuasca analogue felt healthy and enhancing the experience/healing in my brief time of experimentation almost 2 years ago. This species is hyoscyamine dominant for sure.
İf your quest is only to reduce nausea, then there should be much less complicated or risky plants that can do the job. Datura will bring much more than reducing nausea.
As transform says, you need energetic healing at this point. Sleep well, ground yourself on the earth, eat healthy. Do things that heal you in general.
All about Datura - important safety information
[This Datura FAQ is written by u/AnandaPriestessLove on Reddit from r/Datura, and she generously permitted me to repost it here! I know sometimes the topic of taking a few seeds to potentiate other substances or combat nausea is mentioned, but even small doses such as that are something that...
forum.dmt-nexus.me
The Secret-Alchemist Club Anti-Nausea Shot
The Secret-Alchemist Club Anti-Nausea Shot 2oz Fresh Squeezed Ginger Juice from Juicer [or the juicerless juice method mentioned below] 7 Drops Essential Oil of Lemon 3 Drops Essential Oil of Peppermint 3 Drops Essential Oil of Clove 3 Drops Essential Oil of Lavender 1.) Mix it all up and take...
forum.dmt-nexus.me
Huh, I did not suspect Datura Metel would be scopolamine dominant. With the exception of the violet purple contrast on the flowers, the shape and structure of the flowers, leaves and seed pods appear very close to Stramonium a lot more so than Inoxia or Wrighti, and the seeds of Metel I had were very dark. I would of assumed Metel were to be very much dominant in its hyoscyamine content moreso. Also, doesn't some or a lot of the scopolamine degrade or alkalize into more hyoscyamine as the plants age more? I hear scopolamine has more sedating qualities and hyoscyamine usually more stimulating and hallucinogenic deliriant. I understand both can be very dangerous though and unlike if people were taking these medications to treat something like IBS, there isn't any way to accurately measure the dosage with tropane alkaloids in Datura or other nightshades.
Last edited:
Sabnock1990
Be Your Own Shaman
Anything strong enough with Acetylcholinesterase inhibitive properties, so things like perhaps Lemon Balm, or Citrus oils which contain Alpha-Pinene, Gamma-Terpinene, P-Cymene and other things with Cholinergic effects, Coffee maybe, perhaps some Cannabis because it also has Acetylcholinesterase inhibitive terpenes and even THC itself has some effect there, also eggs (the yolk) which have some Choline which can be processed by the body into Acetylcholine which with Acetylcholinesterase inhibition can allow for greater Choline and Acetylcholine to build up a bit more and overtake the anti-cholinergic effects of the Tropanes. And things can be additive so like if you add a few sources of Acetylcholinesterase inhibitors together they will synergize and potentiate the pro-Cholinergic effects of each other so it makes a greater Cholinergic impact than anything on it's own. But anything that's got Acetylcholinesterase inhibition would possibly be antidotes to anti-cholinergic poisoning. Syrian Rue and Harmalas also have Acetylcholinesterase inhibitive properties btw.
I don't know how much of it is caused by it's acetylcholinesterase inhibitor property, but Syrian rue brings me back to myself after any disturbance, be it psychological or herbal/chemical.
Yes, metel is clearly sedative in contrast to the stimulating and lucid (in proper doses) stramonium. They are extremely different ime.
I don't have Syrian Rue and not really sure where to find it in my area. I have several supplements that work as cholinesterase inhibitors such as Ginkgo Biloba, Huperzine A, and Bacopa. I have other calming herbs such as Passion Flower, Lemon Balm, Lavender, and Hops. I occasionally take Psilocybin mushrooms and I smoke Cannabis regularly. I have Kanna and Lions Mane as well. Actually, lately I have had very good results with Ginkgo, Kanna, and Lions Mane. I know Lions Mane helps to create nuerons and supports neuroplasticity, I think possibly Lions Mane may be a cholinesterase inhibitor as well. Anyways, I am starting to feel better, my mind is now more clear with less confusion and able to focus more positively.
I have tried Amanita Muscaria once last year and did enjoy it a lot, also found it to have a really good synergy when combined with psilocybin. I am not sure where to find it now though, I have read that Muscimol may very well have an upregulating effect on muscarinic choline receptors along with it's GABA agonism. I have only been able to find Muscaria so very occasionally though.