this is what i find as well, and the only way i have used calamus.  i have taken it by itself on a hike, and by swallowing the juice/saliva i didn't get thirsty, ( i had run out of water) and i also think it helped suppress appetite.

i have also chewed it in combo with psilocybin and mdma.  i found it very synergetic.

no idea what compound causes the nausea--never heard of anyone getting sick on calamus until now.

phlux said he swallowed the rhizome and got sick and swiy did a acetone extraction, so would it be probable that the mystery compound is not water soluble?