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Acorus gramineus safety question

midnight490

midnight490

Rising Star
Hi everyone, Acorus gramineus is an instant stimulant that I have used for sublingual chewing alone and it is very effective! I have some questions about Acorus gramineus, I would like to use it for making and inhaling, mixed with Centella asiatica. I am taking Rhodiola rosea with 5%rosavin every day, rosavin is a kind of maoa, is it safe?
 
Here's a review article which came up when using the following search terms: Acorus gramineus adverse reactions interactions
I'd caution that some of the chemical structures (and/or their names) in the article are erroneous, which betrays a lack of understanding on the part of the author(s). Hopefully the ethnomedicinal information they present is more reliable. In that respect, calamus is presented as generally safe, despite asarone being highlighted as a potential hepatic carcinogen.

All that says nothing about the potential for interaction with rhodiola, so I'd looking very carefully at how acorus may interact with monoaminergic systems, and exactly what kind of MAO-a inhibition rosavin produces.

If you decide to proceed with the combination it should go without saying that you'd begin with tiny doses and remain vigilant of the effects - all while trying to remain free from hypochondria and other neurotic biases! I can't make any recommendations, but it looks as though the neuroprotective effects of these two herbs may be complementary.
 
Transform said:
Here's a review article which came up when using the following search terms: Acorus gramineus adverse reactions interactions
I'd caution that some of the chemical structures (and/or their names) in the article are erroneous, which betrays a lack of understanding on the part of the author(s). Hopefully the ethnomedicinal information they present is more reliable. In that respect, calamus is presented as generally safe, despite asarone being highlighted as a potential hepatic carcinogen.

All that says nothing about the potential for interaction with rhodiola, so I'd looking very carefully at how acorus may interact with monoaminergic systems, and exactly what kind of MAO-a inhibition rosavin produces.

If you decide to proceed with the combination it should go without saying that you'd begin with tiny doses and remain vigilant of the effects - all while trying to remain free from hypochondria and other neurotic biases! I can't make any recommendations, but it looks as though the neuroprotective effects of these two herbs may be complementary.
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Oooooh. I noticed that this article mentioned that it is a non-selective 5ht inhibitor, which seems to be consistent with the experience mentioned in "69bon". If it is true, my behavior will be very dangerous, which will lead to severe serotonin syndrome and severe vomiting reaction.
Thank you for helping me check the information! I'll start with a low dose to understand the synergies between them
 
midnight490 said:
Oooooh. I noticed that this article mentioned that it is a non-selective 5ht inhibitor, which seems to be consistent with the experience mentioned in "69bon". If it is true, my behavior will be very dangerous, which will lead to severe serotonin syndrome and severe vomiting reaction.
Thank you for helping me check the information! I'll start with a low dose to understand the synergies between them
Click to expand...
It kind of depends on the type and efficacy of the MAO inhibition by the rosavin. It doesn't appear to activate oral DMT particularly effectively, for example, which in this case could be considered a good sign.
 
Transform said:
It kind of depends on the type and efficacy of the MAO inhibition by the rosavin. It doesn't appear to activate oral DMT particularly effectively, for example, which in this case could be considered a good sign.
Click to expand...
Yes, you're right. I just tried taking acacia bark alone tonight. For example, I normally take 1 gram of harmala and 1 gram of bark and it works for almost three hours. But rosavin, I've been eating it for four days now, and I can only feel the taste and physical sensation of dmt for five minutes tonight, which is funny.
 
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