At pH 8.5 the liquid does become cloudy. However, even after 1 month in the refrigerator, no bufotenine crashes out. The bufotenine stayed as a suspension. Maybe you need a centrifuge? SWIM does not have a centrifuge anymore and is not planning to get a new one.

Bufotenine is soluble in acid and alkali. The reason it's soluble in alkali is because of the hydroxyl group.

There are many alkaloids present in yopo, nearly a dozen. It could be any one of the alkaloids that crashed out in your friend's tests.

SWIM tried this, but without a centrifuge and it never worked at any pH for bufotenine. Maybe the amount of water used was in excess?

Now that SWIM has found a simple way to obtain 98% pure bufotenine, the next time he does an extraction he can test this out with a few grams of pure clear bufotenine crystals and see exactly what happens at different pH levels in water. Without the other compounds present, if anything precipitates he will know for sure that it is bufotenine and nothing else.

SWIM is also planning on adding salt to the water to see if that helps.