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Anandamide, endogenous cannabinoid?

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tigerstrike92

tigerstrike92

Homo-divinorum
Has anyone ever had any experience with anandamide? It is an endogenous cannabinoid, much like how DMT is an endogenous tryptamine. So who knows, maybe it might have some profound effects?

I have never heard anything about it being used exogenously, so thoughts?
 
I thought i read somewhere that anandamide was confirmed not to be in chocolate, and that there were 2 other cannabinoid mimmics that might act on those receptors.

I'm talking about the raw chemical, completely by itself.
 
tigerstrike92 said:
Has anyone ever had any experience with anandamide? It is an endogenous cannabinoid, much like how DMT is an endogenous tryptamine. So who knows, maybe it might have some profound effects?

I have never heard anything about it being used exogenously, so thoughts?
Click to expand...
Somebody with real knowledge of biochemistry, i believe it was either infundibulum or entropymancer, told me that this chemical doesn't pass the brain-blood barrier. So eating lot's of chocolate will not help you replace cannabis.
 
..click the anandamide link when the window opens.

It does cross the BBB at least when cacao is ingested..there is not alot of anandamide present in cacao though. Although there are many differeent strains of cacao and I have an heirloom strain here..a HUGE box of it from central america and it might have higher ammounts of everything. I doubt that these tests done on "chocolate" have been done on raw unprocessed heirloom beans that the mayans etc use. Cacao is definatily either more than just theobromine, or theobromine is NOT pharmacologically the same as caffine like some say..if you take enough of the raw beans it is definatily mildly stoning and has a distinct phen feeling to it. You have to have raw cacao beans for it to really work though, the processed dark chocolate will not act the same way for me and feels just sort of stimulating.

I bet also that the small ammount of anandamide that is active in the chocolate that has been tested is somewhat enhanced by the other alkaloids present. Either way since cacao contains alkaloids that inhibit the breakdown of anandamide I would think one should be able to ingest cacao and then take anandamide.
 
There's lot's of stuff in cocoa. Much more than just caffein or theobromin. I have noticed these phenethylamine-like effects as well and i think it's the combination of all those substances that causes these effects.
 
So If I had some raw organic cocoa nibs, how many would I need to eat eat to notice the phenethylamine effects?
 
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