I did a lot of research (including these forums) on all four combinations and could only find mentions of nootropics possibly potentiating tryptamines and phenethylamines. I also found mostly positive or neutral trip reports. I have also read a couple of times there is very little research on nootropic/drug combinations however the info I had found lead me to beleive it was safe. I guess there is now at least one negative case. I am glad I live to share the experience