No one can tell you if you are ready but you. I have been practicing a lot of classical yoga, various limbs, changed my diet, changed behaviors, I have not had a bad day at work in over 2 weeks, I feel vibrant, my skin feels cool and electric, and life feels easier and easier every day. I recently made an incredible batch of changa that I am dying to try, or would be if I let myself think about it too much, but I do not feel ready to try it. Maybe deep down I just have no desire to visit that space right now, or maybe I still need to work on something, maybe there is one little piece of a lesson that I still have not figured out, and so I have a certain spark of dissonance that I can feel and has me a touch uneasy to face the void again, or maybe something else requires my attention. Who knows? Something isn't quite right for it though, for me, and so I'm not even thinking about it because I will drive myself crazy until I decide to jump and then will probably just shut myself out lol.
I don't know what makes it the right time for another, or for myself even, not really. I do have a pretty keen sense of red flags though and when I should probably being doing something else with my mind and time. It sounds like you have some things to work out in the everyday waking world and maybe attend to that until you are in a comfortable enough place that you can give your attention to the medicine. But then again, maybe not. I think for harm reduction's sake, the best advice you are going to get around here is take some time to work on you and your circumstances. The reality is that we just don't know, but it does sound like there are pressing matters to attend to and maybe hyperspace can wait while you handle that. It's definitely not going anywhere.