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Antidepressants and MAOI

Migrated topic.

Fernape

Rising Star
SWIM is on Lexapro antidepressants (10mg per day). Is it dangerous to take DMT orally with an MAOI while on Lexapro? How many days should SWIM go without the medicine before taking DMT orally with an MAOI? I've read that it can be lethal.
 
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What is the danger of a smoked MAOI (reduced caapi brew / changa) with a SSRI or SNRI? Does smoking caapi infused leaf pose s significant risk to someone on one of these medications?

Thanks!

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K
 
Agreed. Even with RIMAs like the harmalas or moclobemide, having that compound in one's body together with any serotonin reuptake inhibitor, whether selective or not, is simply unacceptable regardless of the method of administration. As is sudden discontinuation of the SSRI or SNRI. If the activity in the CNS is high enough to potentiate DMT, then it must be assumed to also be high enough to potentiate serotonin reuptake inhibitors.

Perhaps consider exploring the world of changa and enhanced leaf. Many people report that Electric Sheep is as powerful a teacher as the harmalas, and it should be safe with antidepressants. Starting with a low dose and carefully observing for side effects or interactions is definitely prudent, but problems are unlikely to occur.

Working with any form of spice, whether or not its allies are included, may help people to stop needing antidepressants. The effectiveness of work with entheogens varies from person to person, but many people do report great results. I long for the day when psychedelics are once again counted among the medically recognized possibilities for dealing with mental health problems.
 
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