... thinking aloud . I bet Psilocybin would need way less MAOI than with dmt. Aren't there any tales to tell from our most ardent psychonaut members..!? Let's hear more psilo-pharmahuasca stories .! But I feel I should remind us, from my once-newbie experience, that the subtle effects of the MAOIs in rue seed and capii are not to be mistaken for a 'weak' biochemical effect. Rue seed b-carbolines are potent MAOIs, totally shutting down the clean-up of dmt, psilocybin, LSD and other tryptamines ! ... Some where, someone suggested 200 mg of b-carbolines are in just 3.5 g seed (extracted). A dose of 3.5 g rue seed probably doesn't shut down every one of your MAO enzymes, but it gets pretty close for a 150 lb person, lasting 2 - 4 hours. The thing is that you can't feel the total-enzyme-shutdown until you take a tryptamine, and when you do, the alkaloid just cruises around in your body not getting removed. on > 100 mg dmt you might surf in imagination soup, with no land in sight for quite a awhile... then finally, AHOY ! .. (... puking is optional) you'll find a piece of dry, MAO-active land ! I remember "wanting my enzymes back" ... ! But with 150 mg dmt I knew it was going to 'end' .. I figured (while blazingly high in synesthesia soup and OEV/CEV), that dmt was an endogenous tryptamine, so lucky me it was going to be cleaned up ASAP, once MAOs came back on-line ..>! But with psilocybin + MAOIs I bet it'll take longer to 'come back / down' ... I wonder what amount of rue extract is needed to close-down all your MAO enzymes..? I hope to find to an optimum balance of MAOI to dmt - anyone know if it's better to eat a little more dmt and less MAOIs...? Try 3.5 g of rue seed as a strong MAOI dose - (EXTRACTED and filtered) - on an empty stomach. The body and brain immediately pick up the b-carbolines, and you'll feel greatly mellowed in 15 min, some subtle hypnogogic-like CEVs. YOu'll sleep well and wake up feeling 'un-depressed'. To test rue-extract alone, I've considred doubling the dose to 7.0 g of lemon-juice extracted seed, as it could be more closed-eye visual. But with Dmt or psilocybin watch it with the MAOIs !