[quote:f99d245884="Noman"]Well, the jury's still out on whether bufo is completely undesirable though I'm not really after it. I'm more interested in converting it through heat treatment or enzymatically. Of course if I could just isolate it, then it stands to reason that the residue would contain the other alks if present.[/quote:f99d245884]    I've had a few experiences with  yopo cebil. I wouldn't say that it's (bufotenin) undesirable!       It's pretty intense though, you do get pressure in your head and something of a sinus infection for a few days after insulfation. But I had visuals every time and an OOBE too, on one occasion!     It has some value as an enthoegen. Don't rule it out. It's not for the faint of heart though! yopo was a little frightening to me every time I used  it!     I'm still interested in yopo, although next time I think I will experiment with yopo vIlca (peregrina) as opposed to cebil.