The short answer is no, or else it wouldn't be used as a main ayahuasca admixture plant for that very reason. But I've not heard any negative reports of Chali-changa. Regarding the presence of other alkaloids, the jury is still out on that. Samples of Chaliponga have been analysed by a Nexian via GC-MS and no traces of 5-MeO-DMT were found.