Well you do need to add 6% calcium hydroxide by weight to the resin to get it to work well sublingually (or as snuff), so the DMT in the resin definitely needs to be freebased first. But nothing else is needed. It works really well.

Perhaps the calcium hydroxide is the KEY?

SWIM is not too fond of DMSO. He has some and tried dissolving DMT in it and didn't get much effect from it. He also tried freebase bufotenine (which works well sublingually on it's own) in DMSO, and it didn't work any better than plain bufotenine. DMSO is way overrated.

I imagine 500 mg of resin at most might contain as much as 10% DMT, but it's probably more like 5%. Even at 10%, that's only 50 mg of DMT. That's not enough DMT to do anything. But the resin clearly works and the effects are that of DMT. It's a mystery. There's something in it that's aiding it's absorption I'm sure of it.