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beta-caryophyllene has been shown to bind to CB2 receptors.[URL unfurl="true"]http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2449371[/URL]So far no essential oils have been shown to bind to CB1 receptors (doesn't mean they all don't however no one has found any that have and people are looking). There was suspicion that thujone (the stuff in wormwood) acted via CB1 but in vitro studies showed it only very weakly binds to the CB1 receptor. Very weakly. The doses needed to interact in the body would be dangerous as thujone is quite toxic.
beta-caryophyllene has been shown to bind to CB2 receptors.
[URL unfurl="true"]http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2449371[/URL]
So far no essential oils have been shown to bind to CB1 receptors (doesn't mean they all don't however no one has found any that have and people are looking). There was suspicion that thujone (the stuff in wormwood) acted via CB1 but in vitro studies showed it only very weakly binds to the CB1 receptor. Very weakly. The doses needed to interact in the body would be dangerous as thujone is quite toxic.
