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Datura + Mda???

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imPsimon

Rising Star
Hi!

Do anyone have any experience with the mix?

Would 3-5 seeds potentiate the effects of some mda?...or mdma

I only have some 90mg and I could use a little boost

=)
 
I don't know about Datura, but I for sure know that a bit Cannabis will potentate both MDA and MDMA to an extreme degree. It will also alter the feeling, but so will Datura... Good luck!

Godt nyttår! ;)
 
Small amounts of Datura stramonium seeds (about 1-5) potentiate LSD, mescaline, psilocybin, bufotenine, and most other psychedelics. With mescaline being structurally similar to MDA, I would imagine that Datura stramonium seeds would potentiate it as well. But Datura inoxia seeds would likely bring the experience down a bit like they do with mescaline. The two are very different. Datura stramonium seeds contain mostly hyoscyamine which is a stimulant, while Datura inoxia contains mostly scopolamine which is a sedative. Datura stramonium seeds are better for potentiating the effects of other psychedelics.
 
69ron said:
Small amounts of Datura stramonium seeds (about 1-5) potentiate LSD, mescaline, psilocybin, bufotenine, and most other psychedelics. With mescaline being structurally similar to MDA, I would imagine that Datura stramonium seeds would potentiate it as well. But Datura inoxia seeds would likely bring the experience down a bit like they do with mescaline. The two are very different. Datura stramonium seeds contain mostly hyoscyamine which is a stimulant, while Datura inoxia contains mostly scopolamine which is a sedative. Datura stramonium seeds are better for potentiating the effects of other psychedelics.
Because MDA is not a real psychedelic like mescaline is, i think that it's harder to exactly predict what would happen.

Datura stramonium makes mescaline more psychedelic, more colourfull.
But because MDA is somewhere in between psychedelic and euphoriant, i think that you wouldn't get the desired effects from datura potentiation, since if you wanted a full psychedelic effect you wouldn't have chosen MDA in the first place.

The best potentiation for euphoriants that is safe, is caffeine. It works so well that most pill manufacturers already put caffeine in their pills.

Euphoriants are often more dangerous in combination with other substances than most psychedelics are.
MAOI potentiation is out of the question.
 
Why??? WHY???

Why is everyone interested in mixing Datura with any drug they come across?

MDA is MDA...if you want to potentiate that take some piracetam and melatonin for about a week before...you'll see some serious potentiation. This mix works well with all Phen's I've tried, from Mescaline to 2C-x to MDMA, to MDEA (yuck), to MDA.
 
Thank you for your answers!=)

I'm not really looking for a psychedelic boost just a boost in general.
90mg is not that much for me, 140mg is what I had last time and that
was a very good dose. Not to strong or to weak.

I thought that stramonium seeds seems to change the experience for lots of serotonin based
drugs that it might just make it something "extra"

Don't like to mix things with cannabis, I like my head "clear".
As for caffeine, it just gives me to hard of a come down.

"Why???WHY???"
Because it's the only thing I got lying around=)...and also it seems to "potentiate" a lot of drugs

...just moved yesterday, don't even have a fridge...or oven...or stove=(
...I'm glad I have my rice cooker. It's my best friend and I see him every day=)

Happy new year to you all! Godt nyttår!! Gott nytt år!!

...I'm of to "the villa" =)=)=)

I think these guys are playing to night, not sure though
 
acolon_5 said:
Why??? WHY???

Why is everyone interested in mixing Datura with any drug they come across?

In small doses it goes well with nearly everything, and it’s CHEAP. That's why.

Datura stramonium, in small doses, potentiates nearly every psychoactive there is, even cannabis and harmala alkaloids. It also potentiates opiates, coffee, pain relievers, etc., etc., etc. It’s a great additive as long as the dose is very low.
 
acolon_5 said:
Take some piracetam and melatonin for about a week before.

This sounds very intersting! !
But taking for 7 days prior to the trip is necessary?
How about one day ?

And how differeent piracetam and melatonin are ?
Are they just potentiate or change the quality of the trip?
 
69ron said:
acolon_5 said:
Why??? WHY???

Why is everyone interested in mixing Datura with any drug they come across?

In small doses it goes well with nearly everything, and it’s CHEAP. That's why.

Datura stramonium, in small doses, potentiates nearly every psychoactive there is, even cannabis and harmala alkaloids. It also potentiates opiates, coffee, pain relievers, etc., etc., etc. It’s a great additive as long as the dose is very low.
The thing is that it also alters the effects of most of these substances.
If MDA would become more psychedelic (and more foggy), why not just take a real psychedelic like mescaline in the first place?

My prediction is that you get a more foggy experience like with cannabis.

The serotonin action of MDA is totally different from that of substances like mescalin and LSD.
To expect a simmilar synergy is based on a wrong assumption.

Maybe taking the amino acids tyrosine and tryptophan would be a good idea. They are metabolized into dopamin and serotonin.
Those are the neurotransmitters that are dramatically increased by this substance.
 
Don't knock it till you try it.

I'm not interested in MDA at all, but I'm fairly confident that Datura stramonium seeds will boost the effects. It might not be in a desired way, or it might be (as in the case with mescaline). Until the combination is actually tried, we won't know.

The main active alkaloid of Datura stramonium is hyoscyamine. Hyoscyamine blocks the action of acetylcholine but is also partially a serotonin antagonist. So it might add some very interesting effects. MDA also affects serotonin. So there will be definite alterations in the effect when MDA is combined with Datura stramonium.
 
Oh, i didn't know it was a serotonin antagonist.
Well, then it will certainly alter the MDA experience.
MDA increases serotonin, wich is responsible for it's euphoriant effects.
They will be diminished, is still my prediction.

This also explains why it enhances the effects of psychedelics.
They stimulate the 5-ht-2a receptor wich leads to a decrease of serotonin in th brain and temporal serotonergic activity via downregulation of serontonin receptors.
The effects of MDA and classical psychedelics are thus completely opposites in this way.

You're right that, until someone tries it, we won't know.
But my instincts tell me that it won't lead to very spectacular results and less euphoria.
 
polytrip said:
You're right that, until someone tries it, we won't know.
But my instincts tell me that it won't lead to very spectacular results and less euphoria.

Well, it’s my understanding that the mild euphoria Datura stramonium produces is from it’s serotonin antagonism, and that the hallucinations it produces at near fatal doses are also from this. It’s other main effects are from it’s anticholinergic effects.

The euphoria Datura stramonium produces is enhanced when it’s mixed with mescaline. I believe both mescaline and MDA produce very similar euphoria and this euphoria is serotonin based, just like that of Datura stramonium. So if you get enhanced euphoria when you mix mescaline with Datura stramonium, I don’t see why you wouldn’t get enhanced euphoria when you mix it with MDA, considering their euphoria is based on modifications of serotonin. Sure they work in different ways, but they both produce serotonin based euphoria. I think it would increase the euphoria of MDA more than it does for mescaline because of the fact that they both cause serotonin euphoria by different mechanisms.

I’d really like to see if my reasoning is correct or not. Too bad no one is testing it out.
 
Meth can be a nice setup for LSD. I wont recommend it on this board. I said to much already..and thats a shame.
Any one got a extra piece of bubble gum? Can you give me a ride home from school?:oops: :cry:

No disrespect to the OP it should work fine with any amphetamine skeleton. Just be careful, I know you will:) :)


Peace
MV
 
MagikVenom said:
Any one got a extra piece of bubble gum? Can you give me a ride home from school?:oops: :cry:

I don't understand. Am I missing something here? Are you saying the OP was done by a kid?
 
I dont fully get that either..
but yeah there is the odd person that I could see comming on here and reading that and thinking how cool it would be to now go smoke some meth and then drop some blotter just becasue someoone at the nexus said that it could be good..

I think that is what MV is referring to...we do need to be careful here becasue there are lots of people that reads these boards and no doubt some of are probabily kids.
 
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