In my experience, there is no getting away from fear in a high dose oral trip. The mind can go in to chaos and confusion, and the body can get confused as well. I think it's the interaction between the maoi and the dmt, as I've found smoked trips to be not similar to oral trips. There is no way out. I've found that the body and mind react on their own, whether I want to do anything about it or not. I've been terrified on oral trips, but I just lie there like nothing is wrong. When I'm at the peak of it, I can sense that it's just energy running through me, and my body and mind deal with it in its own way... it plays out as my trip. There's nothing I can do about it. I guess that's a form of acceptance, but there are times when my body or mind says to get scared, so I do. And the fear just feels like the body's way of dealing with this energy that's going throgh it. Who am I to direct this energy that's become more powerful than my will? I am floored and flat on my face. Let it do it's thing and just keep breathing.
I've found the best thing to do is just close your eyes and lie down. But then.... there are times when I feel commanded to open my eyes and look around to scan the environment and get my bearings and keep myself conscious. When that happens, I just listen to the body. The last dmt trip I got scared and I encountered a mocking voice telling me, "you fool... did you really think you could do something like this and not get scared. Sorry, but fear and bad stuff is a part of life. Get used to it and face me."
To me, there's little point in trying to remember anything safe and comfortable because in a confused state, you forget what you're supposed to be doing anyway. One minute you're focussed, the next you're gone, and it can come to a point where the thing that was supposed to give you comfort, just becomes confusion itself... and that is really scary. If it comes to a point where you don't even know what you're supposed to be doing anymore, or who you are, how are you going to calm yourself down? You'll start grasping at something, and then realize you don't know what you're grasping for. But, general survival instinct still remains even in the most confused states. I know I need to breathe, I know I need to avoid predators, or attacks, and I know that in my intoxicated weakened state, my best bet is to just lie down and avoid all conflict, plus I can barely walk anyway. So I just lie there and keep breathing, and wait for something familiar to come along. But even then, you can still get scared. When I get really confused and think I might actually be dying, I tell myself, "just keep breathing, and you'll be fine"... but then sometimes it gets to a point where even my breathing becomes hard to focus on, and I'm not sure if I am really breathing right, or if I'm on my way out. What are you going to do when you're not even certain about your most basic function? You'll have nothing else to turn to for comfort. The only thing you'll have to turn to for comfort is if you manage to remember that people aren't dying from taking dmt, and you are probably just imagining that you're dying. But that probably won't provide you with much comfort because everything in you will be telling you that you're dying, so unless you're cool with that, you better try as hard as you can to stay alive because there is nothing else for you to do at that moment.
But of course, you wouldn't be the first person to think they're dying while on a psychedelic. That just seems to be a common experience among users, but people live through it. I don't know of anyone dying fom ayahuasca. Eventually, something familiar comes along, it doesn't matter what it is. I'll look up and notice something about the sky and realize what time it is, and realize, "YES!! I just made a logical conclusion, I'm starting to remember my senses". The body and mind will go through its own natural process of losing itself, getting confused, and eventually coming back to normalcy. It will happen on its own.
The best thing to do to avoid panic is to be in a place where you won't have to deal with anyone or anything. But even in the safest environment, your body and mind WILL go in to chaos if you take a high enough dose. Just make sure you are in a place where you won't have to deal with any distractions because in your intoxicated state, having to deal with anything will be extremely difficult and probably very.... un-nerving.