DMSO for delivery???

[antrocles]

here's one for our beaker-stirring brethren (benzyme, bufoman, 69ron, et al..) :

i have been using DiMethylSulfoxide (DMSO) for various therapeutic purposes for a little while now. i use it topically AND in small amounts mixed with a liter of water and 1g MSM internally. it seems to be working pretty well to improve flexibility, flush out calcium and accumulated lactate from my muscles, etc...

so- naturally i've researched it pretty extensively....especially since it's pretty controversial even to this day. the thing is, it's considered a MAJOR solvent. as in, you can't even put on clothes over where you applied it topically until it is fully dried or you will absorb any dyes/perfumes/detergents that are on your clothes DIRECTLY INTO YOUR BLOODSTREAM! this stuff is like a point-to-point bullet train taking ANYTHING you dissolve into it DIRECTLY into your bloodstream....

...i think you can see where i'm going with this....


let me put it this way: when i put it on, say, my calf muscle...within 30 seconds my breath begins to smell like sulfur. this stuff gets into you so fast...it's almost like...when you....smoke....spice....

here's a potential scenario (providing freebase spice dissoLves in DMSO...but i'd be willing to bet it does) - take a sublingual 200mg THH dose, hold it for 20 mins, wait another 15 mins or so after you've swallowed....take your spice dissolved in a tiny amount of DMSO, put it in a little spray bottle and spray it on a large surface area of the body like your stomach....

COULD IT WORK??

my curiosity is beyond piqued...

LOVE AND GRATITUDE!!

 

[burnt]

I am fairly certain there have been some threads on this in the past. I forget where though...

 

[Infundibulum]

DMSO does not work for spice; SWIM has used it to deliver up to 200mg of freebase spice with no effects whatsoever.

It may work however in combination with harmala alkaloids, but SWIM sees not the benefit of this.

Also, why does SWIY's DMSO bring the garlicky smell in the mouth? SWIM has heard this mentioned before but SWIM never gets it when DMSO is applied on the skin. But SWIM's DMSO is the purest grade available, used for long term storage of human oocytes and embryos. It could be impurities due to its manufacture that may be responsible for the garlicky taste.

 

[69ron]

SWIM has 99.9% food grade DMSO. It can easily dissolve freebase DMT at 20 mg/ml. Many have tried transdermal application of it with no effect whatsoever. SWIM has tried it sublingually up to 20 mg dissolved in 0.5 ml DMSO with 30 mg citric acid (forming DMT citrate which is more soluble in DMSO than freebase DMT is) and there was only very slight effects from it. It’s a waste of DMT.

When SWIM smokes 20 mg without THH or takes 20 mg orally with 200 mg THH he has very strong visual and psychedelic effects so there’s no benefit to using it in DMSO because DMT just doesn’t absorb well sublingually or transdermally even in DMSO.


On the other hand, DMSO is a great solvent to store your DMT citrate in for oral ayahuasca use. The DMSO acts as a preservative. The fact that you can dissolve more than 40 mg of DMT citrate in 1 ml of DMSO makes it great for putting in a dropper bottle where one dropper full is normally 1 ml. Stored in DMSO in an amber dropper bottle, DMT citrate should keep for many years.