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DMT AND TURKEY...

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ok. so... L-tryptophan (the chemical in turkey that mes you sleepy). l-tryptophan gets broken down (and yada yada yada) which ends up as trypamine. does eating turkey effect DMT experiences that any knows of? have i just taken this thoguht a little too far? this is from Wikipedia:

"No matter the source of L-tryptophan, the biosynthesis begins with its decarboxylation by an aromatic amino acid decarboxylase (AADC) enzyme (step 1). The resulting decarboxylated tryptophan analog is tryptamine. Tryptamine then undergoes a transmethylation (step 2): the enzyme indolethylamine-N-methyltransferase (INMT) catalyses the transfer of a methyl group from cofactor S-adenosyl-methionine (SAM), via nucleophilic attack, to tryptamine. This reaction transforms SAM into S-adenosylhomocysteine (SAH), and gives the intermediate product N-methyltryptamine (NMT).[6][7] NMT is in turn transmethylated by the same process (step 3) to form the end product N,N-dimethyltryptamine. Tryptamine transmethylation is regulated by two products of the reaction: SAH[8][4][9], and DMT[4][9] were shown ex vivo to be among the most potent inhibitors of rabbit INMT activity."
 
Interesting concept. Trippin' on turkey...

I don't have any clue about how everything metabolizes but if this is true, I wonder if some harmalas would allow the bio-synthed tryptamines to pass through to the brain.

It might lead to some interesting experiments with the leftovers...
 
Im no expert but i cant see how eating turkey will effect your trip. If it does have the possibility then i would imagine you would have to eat a lot of it:lol: .

Im not one to enter the otherside on a full stomache, plus all the crap that the turkey is cooked prob wont help the trip.

But today is a good day to give it a try......idk. But i cant wait to eat:)
 
ICEKOHLD said:
ok. so... L-tryptophan (the chemical in turkey that mes you sleepy). l-tryptophan gets broken down (and yada yada yada) which ends up as trypamine. does eating turkey effect DMT experiences that any knows of? have i just taken this thoguht a little too far?
Click to expand...
Yes, you actually took it very far!

Tryptophan is an essential part of the nutrition, your body needs it to make proteins. A small part of it is also fed in the the biosynthesis pathways of other tryyptamines (e.g. serotonin, melatonin, dmt, 5meo, bufotenine etc). Your assumption here is all (or most!) of your tryptophan intake gets converted to tryptamine and other tryptamine related compounds? Well, no.

Also, a lot of tryptophan in turkey?!?! tryptophan makes you sleepy?!?! who comes up with these crazy ideas?
 
l-tryptophan does make you sleepy. it''s why everyone gets sleepy and wants to nap after eating turkey. i figured it was a far reach but just wanted to know if anyone knew. thanks for answering my question! happy thanksgiving to all!!!
 
ok. just actually looked it up. it's not. you're right. that's just the old wives tale. but come on guy. seriously? you got all gung ho about this? felt like beating your chest a little, eh?
 
Effects of L-tryptophan on sleepiness and on sleep
Ernest Hartmann
Tufts University School of Medicine and the Sleep Research Laboratory, West-Ros-Park Mental Health Center, Boston, Massachusetts, USA

Abstract

Over the past 20 yr, 40 controlled studies have been described concerning the effects of L-tryptophan on human sleepiness and/or sleep. The weight of evidence indicates that L-tryptophan in doses of 1 g or more produces an increase in rated subjective sleepiness and a decrease in sleep latency (time to sleep). There are less firm data suggesting that L-tryptophan may have additional effects such as decrease in total wakefulness and/or increase in sleep time. Best results (in terms of positive effects on sleep or sleepiness) have been found in subjects with mild insomnia, or in normal subjects reporting a longer-than-average sleep latency. Mixed or negative results occur in entirely normal subjects—who are not appropriate subjects since there is “no room for improvement”. Mixed results are also reported in severe insomniacs and in patients with serious medical or psychiatric illness.
 
THANK YOU! someone else who recognizes that eating turkey makes you sleepy. thing is...this debate is becoming about turkey and not even about spice or the nexus or anything positive or useful. chest beating over turkey? i know i'm not crazy for thinking that turkey makes me drowsy but all i asked was if the metabolites from it could effect dmt. it takes tiny amounts of dmt to get off. so if eating large amounts of turkey (which had tryptophan which metabolically breaks down into tryptomine), i believe that it was a reasonable question. if it takes seemingly minute amounts of these chemicals to effect one's body, anything seems possible.

obviously i was wrong but there's no need to get all high and mighty and say that these ideas are "crazy" and like i'm crazy for having thought this. you are supposed to be an instructor, not a punisher. i asked a question. i didn't accuse you of anything. please don't make asking a question seem like something that's gonna get you mocked or spanked or ridiculed. otherwise, people might not ask questions. and then the inexperienced will just wing it and possibly lead themselves assunder. all i did was ask a question. no need to get all worked up please.
 
Tryptophan is an important amino acid which is found not only in turkeys but is present in all poultry and in similar amounts across the whole range.

It can promote sleepiness but it seems that this effect relates to preferential up-take across the blood-brain barrier caused mainly by the effect of insulin which is secreted by the pancreas in response to the carbohydrates which are usually consumed WITH the turkey.Insulin causes amino acid uptake into muscles (amongst other effects) but other amino acids are taken up by the muscle in much greater quantities than L tryptophan, therby altering the ratio of L tryptophan to other AAs in the blood.This promotes preferential uptake into the brain with the final result being increased amounts of melatonin production in the pineal gland.
 
Just my fruity two cents, I offer this only in context of working with diet to enhance tripping (no judgment, just something to think about! :) :

Compared to turkey, bananas, for example, are full of glucose, tryptophan, enzymes, easily assimilated amino acids, and don't take any extra energy to digest. :) (Durian, too!)

Most sleepiness felt after Thanksgiving dinner is leukocytosis. Most of the immune system is active in the GI tract, and the body normally sends a white blood cell response to help digest cooked food (but not raw food). So the sleepiness is most likely energy being diverted to digestion (consider also the enormous AMOUNTS of food people eat, plus the food combinations)... this is energy that could otherwise be diverted to tripping!!! :shock: Think, for a minute, about how you might feel after eating something like fried/processed/fast food, vs. a bright and crunchy salad--what are your energy levels like?

Easily digested food full of glucose and abundant with synergistic combinations of naturally occurring neuroactive phytochemicals is an excellent way to enhance quality of experience and sensitivity to psychedelics, if anyone is seriously interested in working with diet to tweak the experience.

(on the neuroactive properties of a primate diet in relation to ecstatic states of being)

I'm just putting it out there, because I think it's fascinating, not telling anyone what to do. :) I am a rampant fruit-eater, because it has worked for me. You have to do what works best for you, and everybody is different. :)
 
yes. i love fruit! i know it;s not a lot, but i make sure to eat a couple pieces a day and all i drink is water or water blended with 100% fruit juices. i try to eat a banana or apple or some other fruit right after i dose so that i get a fresh burst right when i start to get off. i also know that psychedelics play hell on my (probably everyones) immune system so some fresh vitamins from fruits and veggies can give your body (and brain) a little pep.


i don't drink soda but every once in awhile now, everytime i do, i throw it away halfway through the drink and feel like ass for the next 2 hours. i try to limit fast food. i work construction so sometimes diet can be a hard thing tho regulate. i'm rarely around a fridge or microwave so i have to pack foods that are already cooked and don't need temperature controls. but i try every way i can. the better care i take of my body, the more it will allow me to do with it.

i think diet is a huge factor to the trip (or any substnace for that matter). i do know that thanksgiving feasts make me sleepy and christmas (and other holiday) feasts don't do that so much. guess that's why it was so easy for me to just go along with the turkey makes you sleepy thought. all good info! thanks a lot corpus...that just made it all click. not turkey alone...not the foods eaten with turkey alone...but a mixture of both creates the perfect little tryptophan ninja to penetrate my fortress! thanks!

gosh i love information...
 
Im sure infundibulum didnt mean bad, ICEKOHLD. You have to see, though, that in this forum we really value that people back up what they say, because we want the information we give out to be as reliable as possible. If people present all sorts of speculations as if its true, and considering this is seen as THE community for information regarding dmt, we have to be very careful with the claims we make.

So, also as UniverseCannon just quoted you, when you make such assertions we would like it to be backed up with evidence or at least good arguments to back it up. There are many many papers out there regarding effects of psychedelics, and I dont recall a single one saying psychedelics will 'raise hell' on one's immune system, so please explain what you mean.

Again, this is no personal attack to you, it doesnt matter who is making the claims, whether its a new or old user, we all have to be careful with reliability of what we post.
 
yes. i see what you're saying. when i say that psychedelics play hell on the immune system, i should have said that they play hell on my immune system. after i trip, i feel weak and halfway sick for a day or two and know of other users who report similar effects, especially with LSD. this may not be scientifically backed, just more off of personal experience. i understand that things need to be backed up but he was jumping me about turkey! i wasn't even trying to misinform people about anything related to the actual drugs or experiences, so i didn't see the need to go pressing for for facts in such a way. to call someone's idea crazy and then tell them to back it up or retract sounds kinda off for me. maybe it was just my ego. if so, sorry. that just didn't sit well with me.
 
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