Yes, if she is perfectly comfortable with the thought of taking this step. I don't see why one should need to "warm up" with all kinds of psychedelics beforehand. DMT is DMT, your mind is your mind, and it doesn't necessarily help to any great extent if you've had experience with the other substances before you encounter the spice.
For her this opportunity came into being without having to get in to other stuff. For others this opportunity comes in to being after getting into other psychedelics first. We're on different paths, and just because many DMT users have had more "experience" before they eventually got this "far" doesn't mean it accounts for everyone else.
Friends of mine have turned people on with DMT with no prior experience with any other drug, nor an interest in doing so. They have just genuinly been interested in getting a solid out of body experience, and this is what they've got through their encounters. If your lovely friend is sure on her intent, and totally comfortable with making this decision I'd say this is by far good enough.
Give her guidance, give her love, give her understanding and provide comfort, humor and support if and when she decides to do this. Much luck to you!