I feel ayahuasca and ibogaine both have vast potential in healing addicts...
The pro-psychedelic plant position clearly is an anti-drug position. Drug dependencies are the result of habitual, unexamined and obsessive behavior; these are precisely the tendencies that the psychedelics mitigate.” -terence mckenna
Psychedelics tend to offer one an ability to review their unexamined compulsive behaviors and habits from an objective standpoint. However these compounds being investigated seem to have other pharmacological properties which aide in treating addiction.
Ibogaine acts on opioid receptors, relieving withdrawal, and it's antagonist action at the NMDA receptor may also contribute to its anti-addictive actions...
DMT acts on more than the 5HT2a/c receptors, DMT also acts via sigma-1 receptor agonism, which has been said to play a role in anti-addictive or therapeutic affects of compounds which hit this receptor site...
Psychostimulant abuse is a serious health and societal problem in industrialized and developing countries. However, the identification of an effective pharmacotherapy to treat it has remained elusive. It has long been known that many psychostimulant drugs, ...
www.ncbi.nlm.nih.gov
Ibogaine is a psychoactive alkaloid derived from Tabernanthe iboga, a plant used in initiatory rituals in West Central Africa. Largely because of ibogaine's status as a Schedule I substance in the U.S., the development of ibogaine's use in the treatment of drug addiction took place outside...
www.ncbi.nlm.nih.gov
Ibogaine in the treatment of substance dependence.
Ibogaine is an alkaloid with putative effect in acute opioid withdrawal. Thirty-three cases of treatments for the indication of opioid detoxification performed in non-medical settings under open label conditions are summarized involving an average daily use of heroin of .64 +/- .50 grams...
www.ncbi.nlm.nih.gov
Treatment of acute opioid withdrawal with ibogaine
Ibogaine is an indole alkaloid derived from the root bark of the African shrub Tabernan the iboga and it has been used for many years as a medicinal and ceremonial agent in West Central Africa. Furthermore, both anecdotal observations and recent studies suggest that ibogaine alleviates...
www.ncbi.nlm.nih.gov
Combating substance abuse with ibogaine
As for ayahuasca, the DMT, the harmine, harmaline, and tetrahydroharmaline have all been shown to be beneficial in helping addicts...
Ayahuasca is a medicinal plant mixture utilized by indigenous peoples throughout the Amazon River basin for healing purposes. The "vine of the soul" or "vine of death," as it is known in South America, contains a combination of monoamine oxidase inhibitors and N,N-dimethyltryptamine (DMT). When...
www.ncbi.nlm.nih.gov
Possible mechanisms of ayahuasca' s anti-addictive properties discussed.
Ayahuasca is an Amazonian psychoactive brew of two main components. Its active agents are β-carboline and tryptamine derivatives. As a sacrament, ayahuasca is still a central element of many healing ceremonies in the Amazon Basin and its ritual ...
www.ncbi.nlm.nih.gov
The Therapeutic Potentials of Ayahuasca
This form of ayahuasca-assisted therapy appears to be associated with statistically significant improvements in several factors related to problematic substance use among a rural aboriginal population. These findings suggest participants may have experienced positive psychological and behavioral...
www.ncbi.nlm.nih.gov
Ayahuasca-assisted therapy for addiction
Substances known as psychedelics, hallucinogens and entheogens have been employed in ethnomedical traditions for thousands of years, but after promising uses in the 1950's and 1960's they were largely prohibited in medical treatment and human research starting in the 1970's as part of the...
www.ncbi.nlm.nih.gov
Psychedelics as medicines for substance abuse rehabilitation
-eg