I believe there are people that 'need' excessively high doses compared to others. I personally need much lower doses but usually with shorter duration. Even common pain pills 1 pill for me is strong enough but requires more frequent redose while others need double the dose but last 'normal' duration. This is with zero tolerance for both experiences.

[USER=10604]@acacian[/USER] I think the maoi dietarty requirements are mainly with pharma maoi. I do refrain from consuming certain things during the 4h window after taking caapi tea but I eat red meat, drink wine, yogurt and cheese all without any health complications and last checkup I was actually healthier than I expected with everything in blood work being in healthy ranges. I have made some poor choices but I am still young so might be a part. (30s) I don't take any opioids or strong stimulants while with maoi but I don't have any other restrictions.

I personally also learned about aphantasia and I personally don't 'see' anything and only have a conceptual understanding of images when eyes are closed trying to visualize something. CEV have always been rare for me and I'd imagine someone with the same condition but lower end of enzymes that consume the compounds can easily require or 'handle' high doses.

When I was younger I would dose higher than required which did help me see things differently. I don't regret the experience but high doses are very unpredictable. I personally blacked out to my physical body but there was no "disconnect" and I would move around and not just "in my mind". Many say they don't move but not everyone has that effect.