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[USER=31620]@modern[/USER] what makes you say that it’s more of an issue with pharma? Whether using extracted harmalas or brewing caapi/syrian rue, the potential issues are still there. They all inhibit mono amine oxidase. And whether it is DMT or psilocybin you are combining it with doesn’t change the physiological risks aside from the fact that a larger dose of MAOI is required to render DMT orally active.. psilocybin being most of the way there.

Also, that’s interesting re: aphantasia.. so you don’t find mushrooms very visual? Or are you just referring to CEV? What about breakthrough doses of DMT?

Anyways, everyone has their preference. There’s nothing wrong at all with using psilohuasca and I can appreciate that its preferred over psilocybin alone for some people.. I just thought I’d throw in the point that it’s not black and white better than increasing the mushroom dose to achieve desired strength. It can impart its own flavor on the experience, and there’s the physiological angle to consider too. It’s not necessarily what everyone is looking for.

With mushrooms alone there is little to no risk of physical adversity if you’ve eaten something or taken a medication that might cause issues when MAO is inhibited.

[USER=37405]@doubledog[/USER] yeah it certainly means no psilocybin goes to waste! What kinds of doses of each do you tend to take for desired effects? Do you have preference between psilohuasca and ayahuasca? And do you prefer Syrian rue, caapi or extracted harmalas to potentiate the mushrooms? Have you noticed much difference between them?

I quite enjoy the combination however I find Syrian rue slightly physically uncomfortable when taken orally (less so with extracts).. and I also find mushrooms have a body load of their own that can be distracting at times. So it’s not a combo I’m personally super drawn to. If balancing the dose between them could remove the body load of larger mushroom doses I’d be interested to revisit it some time.. but I’m also very sensitive to psilocybin so supplementing with MAOI is unnecessary.

Curious whether you guys use it in a similar way with mescaline?

Also I just wanna say I’m not advocating excessive doses of psilocybin or defending Kilindi Lyi.. but to those who haven’t done so before, I’d suggest taking great care when combining harmalas with mushrooms as it can be pretty wild. A lot of people find it a difficult/overwhelming experience. And mushrooms are wild enough to begin with! Of course dose is key here.

<blockquote data-quote="acacian" data-source="post: 3952437" data-attributes="member: 10604">[USER=31620]@modern[/USER] what makes you say that it’s more of an issue with pharma? Whether using extracted harmalas or brewing caapi/syrian rue, the potential issues are still there. They all inhibit mono amine oxidase. And whether it is DMT or psilocybin you are combining it with doesn’t change the physiological risks aside from the fact that a larger dose of MAOI is required to render DMT orally active.. psilocybin being most of the way there. Also, that’s interesting re: aphantasia.. so you don’t find mushrooms very visual? Or are you just referring to CEV? What about breakthrough doses of DMT? Anyways, everyone has their preference. There’s nothing wrong at all with using psilohuasca and I can appreciate that its preferred over psilocybin alone for some people.. I just thought I’d throw in the point that it’s not black and white better than increasing the mushroom dose to achieve desired strength. It can impart its own flavor on the experience, and there’s the physiological angle to consider too. It’s not necessarily what everyone is looking for.With mushrooms alone there is little to no risk of physical adversity if you’ve eaten something or taken a medication that might cause issues when MAO is inhibited.[USER=37405]@doubledog[/USER] yeah it certainly means no psilocybin goes to waste! What kinds of doses of each do you tend to take for desired effects? Do you have preference between psilohuasca and ayahuasca? And do you prefer Syrian rue, caapi or extracted harmalas to potentiate the mushrooms? Have you noticed much difference between them?I quite enjoy the combination however I find Syrian rue slightly physically uncomfortable when taken orally (less so with extracts).. and I also find mushrooms have a body load of their own that can be distracting at times. So it’s not a combo I’m personally super drawn to. If balancing the dose between them could remove the body load of larger mushroom doses I’d be interested to revisit it some time.. but I’m also very sensitive to psilocybin so supplementing with MAOI is unnecessary.Curious whether you guys use it in a similar way with mescaline?Also I just wanna say I’m not advocating excessive doses of psilocybin or defending Kilindi Lyi.. but to those who haven’t done so before, I’d suggest taking great care when combining harmalas with mushrooms as it can be pretty wild. A lot of people find it a difficult/overwhelming experience. And mushrooms are wild enough to begin with!&nbsp; Of course dose is key here. <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite1" alt=":)" title="Smile&nbsp; &nbsp; :)" loading="lazy" data-shortname=":)" /></blockquote>

[QUOTE="acacian, post: 3952437, member: 10604"] [USER=31620]@modern[/USER] what makes you say that it’s more of an issue with pharma? Whether using extracted harmalas or brewing caapi/syrian rue, the potential issues are still there. They all inhibit mono amine oxidase. And whether it is DMT or psilocybin you are combining it with doesn’t change the physiological risks aside from the fact that a larger dose of MAOI is required to render DMT orally active.. psilocybin being most of the way there. Also, that’s interesting re: aphantasia.. so you don’t find mushrooms very visual? Or are you just referring to CEV? What about breakthrough doses of DMT? Anyways, everyone has their preference. There’s nothing wrong at all with using psilohuasca and I can appreciate that its preferred over psilocybin alone for some people.. I just thought I’d throw in the point that it’s not black and white better than increasing the mushroom dose to achieve desired strength. It can impart its own flavor on the experience, and there’s the physiological angle to consider too. It’s not necessarily what everyone is looking for. With mushrooms alone there is little to no risk of physical adversity if you’ve eaten something or taken a medication that might cause issues when MAO is inhibited. [USER=37405]@doubledog[/USER] yeah it certainly means no psilocybin goes to waste! What kinds of doses of each do you tend to take for desired effects? Do you have preference between psilohuasca and ayahuasca? And do you prefer Syrian rue, caapi or extracted harmalas to potentiate the mushrooms? Have you noticed much difference between them? I quite enjoy the combination however I find Syrian rue slightly physically uncomfortable when taken orally (less so with extracts).. and I also find mushrooms have a body load of their own that can be distracting at times. So it’s not a combo I’m personally super drawn to. If balancing the dose between them could remove the body load of larger mushroom doses I’d be interested to revisit it some time.. but I’m also very sensitive to psilocybin so supplementing with MAOI is unnecessary. Curious whether you guys use it in a similar way with mescaline? Also I just wanna say I’m not advocating excessive doses of psilocybin or defending Kilindi Lyi.. but to those who haven’t done so before, I’d suggest taking great care when combining harmalas with mushrooms as it can be pretty wild. A lot of people find it a difficult/overwhelming experience. And mushrooms are wild enough to begin with! Of course dose is key here. :) [/QUOTE]