I think you have the terms mixed up. Reverse tolerance is when you become more sensitive to DMT.

So, of course vaporized DMT will hit everyone if vaped correctly? Reverse tolerance actually enforces that point so I don't see why you made it unless you misunderstood what it meant.

I have seen many people report that after have multiple breakthrough doses that they can breakthrough with less of a dose. It isn't so much in the synaptic sensitivity of the molecule but in the pathways that have been set by synaptic plasticity. If your neuronal pathways were roads, ingesting DMT would be equivalent to building a mass of new roads in fringe areas and then slowly over some weeks the roads fade away, if however there is lots of car activity the roads are strengthened and become more fixed and stable and more likely to have car activity.

As for harmalas, I can see there would be a build up of monoamines due to the pronounced effects on the regulation of genes which would increase half life but I still remember someone saying that after a few weeks of daily dosing he was taking well over a gram of harmalas and getting similar effects to when he first started at 300mg, I just can't find the thread because of the forums inadequate ability to search for related words (ie if you search for harmala it won't show any results for harmaline, which other forums do).

That report probably was a one off though because I have searched and nearly all have report reverse tolerance: "harmine/harmaline tolerance?