OP, you may be falling victim to the marketing ploys of Octavio, Gerry et al, who are trying to push an agenda that legitimizes their profitable toad venom enterprises.
These people have been using psuedo archeology and anecdotal reports to claim a non existent heritage of indigenous and traditional use of toad venom in the Americas, have created a lexicon that synonymizes toad venom with 5meoDMT, claim that synthetic is inferior to a substance that arguably is sourced through animal abuse as well as having a plethora of personal egregious behavior levied against the lot of them individually, from theft to physical,emotional and sexual abuse of patrons. They don't seem to be able to hold power without being corrupted. The problem is they see their corruption as apotheosis.
They are all very loud and visible in their pursuit of profit and power and unfortunately are the mouth pieces many people have their only exposure to a lot of this information through.
But yes, 5meoDMT is perhaps the oldest archeologically substantiated ancient entheogen.