what fractal said... it seems there is a very big variation of dosage when taking pharma. I've had several discussions with people here about this and I've ruled out methods of ingestion, it seems its really about individual sensitivity. For example, Jorkest needs maybe 30mg of dmt fumarate for his pharma trips, while I need at least some 150mg for a decent experience, even more like 200mg+ (even taking in the exact same way as him). At least partly this has to do with personal metabolism. Im attaching a publication to this post that deals exactly with this phenotype variations.
Dissolving both together in juice is also the most effective manner for me, but after a few experiences, I find the taste really repulsive, so now I put them in capsules and poke a hole in the capsule. In this way, it takes longer to hit (like 1hr instead of 30mins), the peak is not as strong (but its neither such a big difference), and its worth it for me because the ease of ingestion and also because taking with capsules gives me no nausea at all, while dissolving in juice and drinking gives me some nausea. I've tried with only harmine, harmaline, both together, full caapi extract or syrian rue tea. With all of them I still needed the large amounts of dmt. I've tried with full stomach, empty stomach, and empty stomach but eating bread with butter just after ingestion. The last one being more effective than the others but not by a big margin.
For some very interesting and unknown (AFAIK) reason, it seems there is less individual variation with ayahuasca (as in, b. caapi and p. viridis brew), than with pharma. There is still for sure variation in ayahuasca but not so huge variation as a 10-fold difference between dosages like in pharma. Whenever I have taken ayahuasca in a ceremony, I have taken similar doses to other people and have had very strong experiences too. I really wonder why is that.
Also like fractal said, pharma is very different than ayahuasca in terms of subjective experience. This is not to say that pharma is bad... I love them both. None substitutes the other IMO, each one has their place in my inner exploration. But I do recommend you try some properly brewed ayahuasca sometime and see how you feel about that compared to pharma
by the way, how was the fumarates made? FASW, FASI or FASA?