Hi all,
There's always a bucketload of ideas for experiments. And it is absolutely amazing when people do such experiments, for instance side-by-side tek comparisons. SWIM is normally full of ideas but as of lately (and gotta say aaaargh! here because this "lately" is dragging for a year now) he has no time and no money to devote in experiments. Still, ideal flow all the time and he often forgets them as well. I thought it would be a good idea to make a thread where people can post their experimental ideas so that others who feel like experimenting can get some idea and in the end bring something back to the community.
The experiments can be categorised in quite a few ways;
1. There can be rough measurement analyses, such as solubility of various dmt salts in solvents. SWIM developed the FASA tek some time ago and the initiative was the he first measured the solubility of DMT fumarate in acetone, IPA, ethanol and methanol.
How about other measurements? how much, say dmt acetate methanol/acetone/MEK butanol/ethyl acetate can hold? Or how much e.g. mescaline tartrate can dissolve in water?Acetone? etc. These tests are of utmost importance and I believe that great breakthroughs in extraction strategies await to be developed.
2. Tek comparisons? We have seen quite a few, often A/B vs STB, but there are so much more to do. Once SWIM found that when dmt fumarate is dissolved in water and it is based with sodium carbonate the freebase dmt crystallises out of the basic solution. Endlessness recently made a comparison between this water crystallisation/precipitation method and the sodium carbonate paste (pulling the freebasse with acetone) method. What is interesting is that when dmt fumarate is dissolved and based with sodium carbonate, the freebase precipitates. When one does the same thing with dmt acetate no precipitation occurs! But on the forums I read some days ago that if dmt acetate is dissolved in water and this is based with sodium hydroxide then the freebase precipitates!
There you have it therefore; since a lot of people (and many teks) produce dmt acetate, it would be interesting to see hard experiments on what can make the freebase precipitate out basic water. One could try other bases like calcium hydroxide and ammonia and see whether crystallisation/precipitation occurs in an aqueous dmt-acetate solution.
3. Bioassay tests + combinations - anything goes here, and this is a well-covered area here in the Nexus.
4. Extraction strategies? SWIM and few others have been thinking of ways to break the mucilagenous gooeyness of cactus, focusing on the use of enzymes. Enzymes that can break down proteins, polysaccharides etc can be purchased and incubated with moist cactus powder. Even malted barley (it has enzymes for protein and polysaccharide breakdown) could be mixed in watered cactus powder and left to "brew" to see whether it reduces the gooeyness.
I would love to see more experiments on MHRB clean-up and fining. Imagine this theoretical tek; Acid cook MHRB, then clean up the brew from tannins, polyphenols and proteins with gelatin fining. Remove precipitates. Then apply a fining agent that attracts negative charges, like isinglass to precipitate more unwanted stuff. Remove precipitates. Then apply a fining agent like bentonite or irish moss that precipitates positively charged particles, such as dmt as it is in acidic solutions and keep the precipitates; then analyse how much of the alkaloids are in the final precipitates and how much is left in the cleared-up brew
5. Other ideas? ron posted about the enteric coating of capsules and it would be great if people experiment to see whether it makes any difference in the assimilation of substances. Tons of to-do ideas here!
Anything else? please share and please EXPERIMENT!!!!!!!!1
There's always a bucketload of ideas for experiments. And it is absolutely amazing when people do such experiments, for instance side-by-side tek comparisons. SWIM is normally full of ideas but as of lately (and gotta say aaaargh! here because this "lately" is dragging for a year now) he has no time and no money to devote in experiments. Still, ideal flow all the time and he often forgets them as well. I thought it would be a good idea to make a thread where people can post their experimental ideas so that others who feel like experimenting can get some idea and in the end bring something back to the community.
The experiments can be categorised in quite a few ways;
1. There can be rough measurement analyses, such as solubility of various dmt salts in solvents. SWIM developed the FASA tek some time ago and the initiative was the he first measured the solubility of DMT fumarate in acetone, IPA, ethanol and methanol.
How about other measurements? how much, say dmt acetate methanol/acetone/MEK butanol/ethyl acetate can hold? Or how much e.g. mescaline tartrate can dissolve in water?Acetone? etc. These tests are of utmost importance and I believe that great breakthroughs in extraction strategies await to be developed.
2. Tek comparisons? We have seen quite a few, often A/B vs STB, but there are so much more to do. Once SWIM found that when dmt fumarate is dissolved in water and it is based with sodium carbonate the freebase dmt crystallises out of the basic solution. Endlessness recently made a comparison between this water crystallisation/precipitation method and the sodium carbonate paste (pulling the freebasse with acetone) method. What is interesting is that when dmt fumarate is dissolved and based with sodium carbonate, the freebase precipitates. When one does the same thing with dmt acetate no precipitation occurs! But on the forums I read some days ago that if dmt acetate is dissolved in water and this is based with sodium hydroxide then the freebase precipitates!
There you have it therefore; since a lot of people (and many teks) produce dmt acetate, it would be interesting to see hard experiments on what can make the freebase precipitate out basic water. One could try other bases like calcium hydroxide and ammonia and see whether crystallisation/precipitation occurs in an aqueous dmt-acetate solution.
3. Bioassay tests + combinations - anything goes here, and this is a well-covered area here in the Nexus.
4. Extraction strategies? SWIM and few others have been thinking of ways to break the mucilagenous gooeyness of cactus, focusing on the use of enzymes. Enzymes that can break down proteins, polysaccharides etc can be purchased and incubated with moist cactus powder. Even malted barley (it has enzymes for protein and polysaccharide breakdown) could be mixed in watered cactus powder and left to "brew" to see whether it reduces the gooeyness.
I would love to see more experiments on MHRB clean-up and fining. Imagine this theoretical tek; Acid cook MHRB, then clean up the brew from tannins, polyphenols and proteins with gelatin fining. Remove precipitates. Then apply a fining agent that attracts negative charges, like isinglass to precipitate more unwanted stuff. Remove precipitates. Then apply a fining agent like bentonite or irish moss that precipitates positively charged particles, such as dmt as it is in acidic solutions and keep the precipitates; then analyse how much of the alkaloids are in the final precipitates and how much is left in the cleared-up brew
5. Other ideas? ron posted about the enteric coating of capsules and it would be great if people experiment to see whether it makes any difference in the assimilation of substances. Tons of to-do ideas here!
Anything else? please share and please EXPERIMENT!!!!!!!!1
