Don't know about it’s solubility, but I do know that DMT phosphate absorbs into the body many times faster than the other forms do. So when making ayahuasca, DMT phosphate is one of the best forms of DMT to use. Better than DMT HCl, DMT citrate, and DMT acetate. I’m not sure why it absorbs so fast. But many ayahuasca users absolutely swear this is the case.