DonPeyote
Rising Star
From Marsofolds Tek:
"Naphtha : the freeze-precipitation technique is a double-edged sword. Very convenient and high quality, but highly dependent upon knowing the approximate amount of DMT expected to be precipitated.
If you use too much naptha, then only a little bit precipitates out. If you use too little, then it doesn't extract it all out of solution. It is the simplest case of recrystalization. The best way using it if you aren't very sure of the yield is to use a slight excess to extract, then evaporate it down to 10% of the original volume. THEN freeze it.
This will pretty much guarantee excellent results. For example: For a pound of rootbark use 500 milliliters of naptha to extract. Then evaporate it down to 50 milliliters. Then freeze it and filter out the crystals.
By the way, you must very quickly filter it within a minute or two after removal from the freezer so it doesn't have any time to warm up. And your freezer can't be marginally cold. If it doesn't freeze ice cream HARD,then it isn't cold enough. -20C is about where it should be."
This finally clicked in my mind. The reason for so many low yield extractions during the re/x phase , was because I had too high a ratio of Naptha to DMT in solution, so it would not precipitate out during the freeze phase. Reducing the volume of Naptha by evaporation to 10% of the extraction volume prior to freeze precipitation will optimize the yield.
Took me a while to finally understand the value of this critical step!!!
DP
"Naphtha : the freeze-precipitation technique is a double-edged sword. Very convenient and high quality, but highly dependent upon knowing the approximate amount of DMT expected to be precipitated.
If you use too much naptha, then only a little bit precipitates out. If you use too little, then it doesn't extract it all out of solution. It is the simplest case of recrystalization. The best way using it if you aren't very sure of the yield is to use a slight excess to extract, then evaporate it down to 10% of the original volume. THEN freeze it.
This will pretty much guarantee excellent results. For example: For a pound of rootbark use 500 milliliters of naptha to extract. Then evaporate it down to 50 milliliters. Then freeze it and filter out the crystals.
By the way, you must very quickly filter it within a minute or two after removal from the freezer so it doesn't have any time to warm up. And your freezer can't be marginally cold. If it doesn't freeze ice cream HARD,then it isn't cold enough. -20C is about where it should be."
This finally clicked in my mind. The reason for so many low yield extractions during the re/x phase , was because I had too high a ratio of Naptha to DMT in solution, so it would not precipitate out during the freeze phase. Reducing the volume of Naptha by evaporation to 10% of the extraction volume prior to freeze precipitation will optimize the yield.
Took me a while to finally understand the value of this critical step!!!
DP