When you say transdermal, do you mean like a dermal gel or patch of some sort?

This is something I've always been curious about, since it would offer a way around the need for MAOIs, and could potentially be engineered for a trip of any length of time.

I believe it was House who posted mention of spilling a DMT rich solution on his arms during an extraction procedure, and tripping hard for a couple hours. So we know that in principle it could work.