AwesomeUsername
Esteemed member
A thought came in my mind when I started analyzing their mechanism of action, and all the contradictions that come with it, not to mention that if you take too much just on its own it could kill you or at the very least severely harm you.
Now harmalas are atypical in their effects making them quite different than other MAOIs, reversible or irreversible, but this still doesn't make me question its safety profile less.
They fall into the category of anti-depressants, and anti-depressants in general have caused some pretty gnarly effects on people. In most cases doing way more harm than good.
Let's take ayahuasca for example. You have a compound that inhibits MAO causing you to inhibit the breakdown of serotonin, dopamine, norepinephrine and on top of all that you add one of the most potent hallucinogens known to man.
This is some serious brain chemistry going on here, which in theory could mess your overall brain chemistry pretty bad and leave you worse off.
Since it is reversible, it is obviously safer than the irreversible ones that tend to do the same for a more prolonged time but it still doesn't seem quite as benign.
It isn't a releasing agent like cocaine, meth or MDMA but I would imagine once the effects wear off you are left with plummeted levels of monoamines making your levels of neurotransmitters lower than they were before you started out.
Doesn't sound good at all, and I'm seriously considering stopping using them altogether, in prolonging tryptamines or on their own. They seem to do more harm than good.
But! I would like to hear a second opinion too, do you guys consider harmalas safe when used correctly or is it just the necessary price you have to take introducing those nasty drugs if you want to prolong your experience with tryptamines?
Now harmalas are atypical in their effects making them quite different than other MAOIs, reversible or irreversible, but this still doesn't make me question its safety profile less.
They fall into the category of anti-depressants, and anti-depressants in general have caused some pretty gnarly effects on people. In most cases doing way more harm than good.
Let's take ayahuasca for example. You have a compound that inhibits MAO causing you to inhibit the breakdown of serotonin, dopamine, norepinephrine and on top of all that you add one of the most potent hallucinogens known to man.
This is some serious brain chemistry going on here, which in theory could mess your overall brain chemistry pretty bad and leave you worse off.
Since it is reversible, it is obviously safer than the irreversible ones that tend to do the same for a more prolonged time but it still doesn't seem quite as benign.
It isn't a releasing agent like cocaine, meth or MDMA but I would imagine once the effects wear off you are left with plummeted levels of monoamines making your levels of neurotransmitters lower than they were before you started out.
Doesn't sound good at all, and I'm seriously considering stopping using them altogether, in prolonging tryptamines or on their own. They seem to do more harm than good.
But! I would like to hear a second opinion too, do you guys consider harmalas safe when used correctly or is it just the necessary price you have to take introducing those nasty drugs if you want to prolong your experience with tryptamines?