I've never put my hands on safrole. But I experienced the psychoactivity of Nutmeg.
A night drinking rum with friends I decided to give a try and ate one or two whole nutmeg, that I grinded beforehand, so they were quite fresh. I didn't notice anything that night as I was so drunk.
I went to bed, and when I woke up the next morning, I noticed afetr two minutes: Hang on! I'm feeling trippy, like a low dose of LSD, or some cacti.
I say this, there was no visual but it wasn't like marijuana at all (or nothing stoned as far as I remember) . So I had a light breakfast and rapidly went out to enjoy this amazingly nice energy. Very creative and full of joke, well energized. And so surprised that a spice found in any food store could be working so much.
I've been lucky to don't be sick that time.
A few weeks laters, I tried again this nutmeg with some Lsa seeds but felt so damn sick, puking so much, I never tried it again (well I think I was mixing a bit of mexican psylocibe with the a bit of lsa), the very stupid attitude of: I have a little of few thing why not smash them up and eat them all to have a decent trip (that was Many Years ago) .
Calamus is working for me, I never got sick with the acetone wash + cold water extraction with 10 grams nor a simple CWE on 10 grams. the taste is better after an acetone wash and goes very well with Vanilla and Cinnamon, Hmmm so refreshing and euphoric drink !
So the question is what wash/extraction could be done on nutmeg ?
Probably a CWE at least.