Just a small account of my experience with moxxy (5-MeO-MiPT)

[Lizz]

I don't see this one very much on here, so I thought I'd write up my experience with it. I did read a bunch of trip reports on Erowid about the stuff, but I found my personal experience with it to be very atypical.
Dose; 20 mg administered by gel cap.
It took about 45 minutes to an hour to actually feel anything (I'm assuming that's because of the gel cap). The first effects I noticed were a heavily sedative body load. I spent a good portion of time laying on my bed in some weird floppy position, feeling like I should be doing something, but having no motivation to move any of my body parts. My thought patterns were highly disordered.

I remember wanting to listen to music but being unable to think of what I wanted to hear. I also felt rather hot and feverish. Having to get up to go to the bathroom caused significant disorientation, I remember stumbling down the hall several times like I was drunk. The visuals came on gradually starting as a strange flickering, almost reminiscent of a silent film, but eventually giving way to the breathing walls and shifting patterns I so love. I was very impressed with the assortment of visuals i got from this substance, especially with eyes closed. The sedative body load persisted throughout the trip.

I also recall the visuals coming in waves which threw me off quite a bit. One moment id be looking around the room and everything would appear normal, and then in a another second it would be like having double vision, or wearing 3d glasses outside of the movies. Patterns were coming out of the walls and the wood grain on the floor with increasing intensity and then would disappear in a flash.


A significant amount of the trip reports I'd read, as well as first hand accounts from friends mentioned the sexual aspect of the substance. I was very surprised that that was essentially nonexistent for me, since most psychedelic substances have that effect on me. Maybe that's just not what I needed at that point in time. I will say that smuggling was probably the best thing in the world. Closing my eyes while embracing made me visualize and feel the other person's energy and mine merging and flowing together and it was just so beautiful to me. If you are in a romantic relationship I highly recommend trying this substance with them.

Another thing I noted was different in my experience than most of the other accounts ive read is that mone had a surprising amount of emotional and perceptual depth. While most reports described the trip as supercicially fun but not all that deep, i had a far more emotional time than the last couple times I took LSD. I laughed. I cried. I had some very earnest heartfelt conversations with people and said things I'd been holding back for months. I came to terms with my shortcomings as a parent and have been trying to implement those revelations in my daily life every day since. All in all this trip was defIntel exactly what I needed and I will be trying this substanve again. It was very intense and i think that 20 mg was the perfect dose.

 

[dreamer042]

Interesting report, thanks for sharing!

20 mg is a pretty sturdy dose with this one. The bodyload is pretty common, as is the wave effect and visual depth you mentioned. I'm quite surprised you didn't get the sooper strong entactogen effect most people report, I certainly get that from this substance. The music enhancement is what really takes the cake for me though, I've never had any substance effect music the way this one does, it very much hit me at the soul/being level exploring soundscapes on this one.

I'm not really surprised at the emotional effect you mention, particularly at that dose. This is one definitely a good time and fairly light as far as mind wobble goes for a tryptamine, but it certainly opens up the empathic circuits if you pursue those pathways with it.

Anyway, great report! I'm glad you got what you needed out of it and looking forward to others chiming in their experiences.

 

[entheogenic-gnosis]

Moxxy?

This is a thread regarding 5-methoxy-N-methyl-N-isopropyl-tryptamine, no?

shulgin comments on 5-meo-MIPT:

EXTENSIONS AND COMMENTARY : Here is a rather fast-acting psychedelic-like drug, with suggestions of LSD action but with essential differences. It has a lot of things going for it. It is short-lived, a virtue in many people's minds. It may vie with 2C-B as a potential aphrodisiac. It is reasonably easy to synthesize. It is of a pretty high potency. The physical side-effects are minimal. These are the positive points.

But there are points that are neutral or actually negative, and they must be considered. A fair number of people who have explored 5-MeO-DIPT have said that there are some uncomfortable aspects with the experience. Not only are there few if any visual enhancements, but the altered state they entered was one that they simply couldn't use. They couldn't make intuitive leaps. That they were wasting their time.

On the neutral, but scientifically exciting, edge there is again some musical sound distortions that remind one of the actions of the analogue without the 5-methoxy group, DIPT. With DIPT, there was a physical harmonic distortion of the sounds that were heard. With 5-MeO-DIPT (again, two isopropyl groups on the basic nitrogen) these perversions involved musical character and interpretation. None of the comments suggested harmonic structure. I do believe that these two drugs, having such an intimate structural resemblance but with their different distortions of music interpretation, would be rewarding to explore more fully with the view of objectively defining these changes. 5-MeO-DIPT is a mixed bag. But it is a bag that I predict will demand a great deal of interest sometime in the future, especially if the erotic enhancement at a low dose proves to be a consistent property.

There is an interesting story associated with the first publication of the chemistry and pharmacology of this compound, in 1981. My co-author was a Michael Carter, in England. We had discussed a number of potentially interesting tryptamines and agreed upon making a small handful to make and evaluate. We had, some six years earlier, co-published a paper describing a new and exciting phenethylamine which we called 2C-B, and we expected to work together, in our separate labs, on a number of research projects. And indeed, I heard from Michael, from a new address, and he sent me his samples and reports of the new compounds we had decided to make, including 5-MeO-DIPT. Our synthetic materials were spectroscopically identical and the human trials had shown that they were very similar. Along with the samples and a letter there came the draft of a possible paper. I wrote back to Michael my own version of the paper, to his new address, and the letter was returned as undeliverable -- no forwarding address available! Again I sent it back, with full first class postage and a clear request to forward it if necessary -- and this time it simply never came back at all.

The issue sat there for a year or two, and I hoped that something would occur. Nothing. I finally wrote to the telephone company in London (Michael had said something about eventually moving up to London) and asked if they could possibly send me the addresses of all the Michael F. Carter that had telephone service in the greater London area. Bless their hearts, they sent back a list of twenty names. And a statement that they were appreciative of having the middle initial, as without that the list would have been in the hundreds.

I wrote to each and every one of these Michael F. Carter the same letter phrased in a way that required no answer if it was the wrong person, but which would inspire immediate answer from the right Michael F. Carter. No answer. Was he alive? Could some unthinkable thing have happened to him associated with his drug experimentation, either personally or legally? There was absolutely no way to tell, so Michael, somewhere out there, if you read this please drop me a note if you wish to and are able to.

So I left the paper pretty much with his ideas in it, crossed my fingers as I used my address for both authors, and sent it off for publication. The paper appeared and I sincerely hope that I did the right thing. -shulgin;TIHKAL

-eg

 

[Lizz]

Interesting report, thanks for sharing!

20 mg is a pretty sturdy dose with this one. The bodyload is pretty common, as is the wave effect and visual depth you mentioned. I'm quite surprised you didn't get the sooper strong entactogen effect most people report, I certainly get that from this substance. The music enhancement is what really takes the cake for me though, I've never had any substance effect music the way this one does, it very much hit me at the soul/being level exploring soundscapes on this one.

I'm not really surprised at the emotional effect you mention, particularly at that dose. This is one definitely a good time and fairly light as far as mind wobble goes for a tryptamine, but it certainly opens up the empathic circuits if you pursue those pathways with it.

Anyway, great report! I'm glad you got what you needed out of it and looking forward to others chiming in their experiences.

Oh yes. I forgot to mention that aspect lol. This occurred a couple months ago so my memories are rusty, but yes. Music was fantastic. Especially Pendulum and similar drum n bass type music. I remember losing myself in one song in particular.. I wish I could remember what it was called...
But anyway I definitely would do it again. I think the main reason that I got such a good experience with it is because of the dose, most of the other reports I read were somewhere in the 6-15 mg range. But I knew I wanted a stronger experience. I definitely would NOT go over 20. That was as intense as it needed to be lol. Thanks for the response Dreames. I hope to have more to contribute here soon ><

 

[Lizz]

Moxxy?
This is a thread regarding 5-methoxy-N-methyl-N-isopropyl-tryptamine, no?

shulgin comments on 5-meo-MIPT:

EXTENSIONS AND COMMENTARY : Here is a rather fast-acting psychedelic-like drug, with suggestions of LSD action but with essential differences. It has a lot of things going for it. It is short-lived, a virtue in many people's minds. It may vie with 2C-B as a potential aphrodisiac. It is reasonably easy to synthesize. It is of a pretty high potency. The physical side-effects are minimal. These are the positive points.

But there are points that are neutral or actually negative, and they must be considered. A fair number of people who have explored 5-MeO-DIPT have said that there are some uncomfortable aspects with the experience. Not only are there few if any visual enhancements, but the altered state they entered was one that they simply couldn't use. They couldn't make intuitive leaps. That they were wasting their time.

On the neutral, but scientifically exciting, edge there is again some musical sound distortions that remind one of the actions of the analogue without the 5-methoxy group, DIPT. With DIPT, there was a physical harmonic distortion of the sounds that were heard. With 5-MeO-DIPT (again, two isopropyl groups on the basic nitrogen) these perversions involved musical character and interpretation. None of the comments suggested harmonic structure. I do believe that these two drugs, having such an intimate structural resemblance but with their different distortions of music interpretation, would be rewarding to explore more fully with the view of objectively defining these changes. 5-MeO-DIPT is a mixed bag. But it is a bag that I predict will demand a great deal of interest sometime in the future, especially if the erotic enhancement at a low dose proves to be a consistent property.

There is an interesting story associated with the first publication of the chemistry and pharmacology of this compound, in 1981. My co-author was a Michael Carter, in England. We had discussed a number of potentially interesting tryptamines and agreed upon making a small handful to make and evaluate. We had, some six years earlier, co-published a paper describing a new and exciting phenethylamine which we called 2C-B, and we expected to work together, in our separate labs, on a number of research projects. And indeed, I heard from Michael, from a new address, and he sent me his samples and reports of the new compounds we had decided to make, including 5-MeO-DIPT. Our synthetic materials were spectroscopically identical and the human trials had shown that they were very similar. Along with the samples and a letter there came the draft of a possible paper. I wrote back to Michael my own version of the paper, to his new address, and the letter was returned as undeliverable -- no forwarding address available! Again I sent it back, with full first class postage and a clear request to forward it if necessary -- and this time it simply never came back at all.

The issue sat there for a year or two, and I hoped that something would occur. Nothing. I finally wrote to the telephone company in London (Michael had said something about eventually moving up to London) and asked if they could possibly send me the addresses of all the Michael F. Carter that had telephone service in the greater London area. Bless their hearts, they sent back a list of twenty names. And a statement that they were appreciative of having the middle initial, as without that the list would have been in the hundreds.

I wrote to each and every one of these Michael F. Carter the same letter phrased in a way that required no answer if it was the wrong person, but which would inspire immediate answer from the right Michael F. Carter. No answer. Was he alive? Could some unthinkable thing have happened to him associated with his drug experimentation, either personally or legally? There was absolutely no way to tell, so Michael, somewhere out there, if you read this please drop me a note if you wish to and are able to.

So I left the paper pretty much with his ideas in it, crossed my fingers as I used my address for both authors, and sent it off for publication. The paper appeared and I sincerely hope that I did the right thing. -shulgin;TIHKAL

-eg

5-Methoxy-diisopropyltryptamine is slightly different than 5meo Mipt. It's not as popular as 'foxy' but they are similar compounds. From what I've read 'moxy' is like a less uncomfortable version of 'foxy.'

 

[entheogenic-gnosis]

Yeah, the excerpt from TIHKAL was regarding 5-meo-DIPT, which was a mistake, I intended to post the excerpt from 5-meo-MIPT, but copied and pasted the excerpt from the wrong compound.

This was the intended excerpt:

EXTENSIONS AND COMMENTARY : In my lecturing at the University, every couple of years or so some student uses the term "more unique than" or "relatively unique." This immediately triggers a reflex response from me, to emphasize the simple definition that something that is unique is something that is one of a kind, and that all one-of-a-kind things are different from all other one-of-a-kind things. All drugs are unique. Every drug is different from all other drugs. 5-MeO-MIPT is unique.

The last two entries in the "Qualitative Comments" section are longer than usual, but even at that they have been trimmed down from reports sent to me that were each of over three pages in length. A thread common to each of them, is the comparison of the effects of smoking 5-MeO-MIPT to those from smoking 5-MeO-DMT. The speed of onset, the intense depersonalization and loss of immediate contact with one's surroundings, the impressive recall of early memories and the significance of these memories, make the drugs appear similar to one another. And the fact that they are of similar potency when smoked (5-MeO-DMT is perhaps a tad more potent) makes the relationship more comfortable. And then, with the eye of a chemist making further comparisons, the whole structure-activity relationship falls into place. The formulae are identical, except that one of the N-methyl groups of 5-MeO-DMT is extended by a couple of carbon atoms, to an isopropyl group in 5-MeO-DIPT. They are almost the same. They have almost the same action when smoked. They are "unique and similar" and together they appear to be quite different from the rest of the pack. Nope, that is just not so! They are totally different from one another.

All you need to do, to see that clearly, is to look at that one additional observation involving oral activity. This drug, 5-MeO-MIPT, is several times more potent when taken orally than it is when smoked. 5-MeO-DMT is much less active orally than when it is smoked. As a matter of fact, it is not active at all when taken orally. No active oral level has ever been found. What a rich area for speculation. Preferential metabolism? First pass goings-on? Chemical change from pyrolysis in the pipe? Different receptors? Lipophilicity? I am reminded of the quote from Mark Twain; "I like science because it gives one such a wholesome return of conjecture from such a trifling investment of fact."

Might the observations of the remaining oxygen-substituted MIPT's provide additional clues? There are four possible mono-methoxylated MIPT's; all have been synthesized and all have been explored in man. The 4-methoxy-isomer was of modest activity and deserves, and has received, a recipe of its own. The 5-methoxy- isomer is the one described here, and is extremely potent (orally, but less so parenterally). But as one goes to the 6- and 7-positional isomers, the two remaining positions, the psychopharmacological activity seems to be lost. This is a humorous reminder of the British idiom, to be at 6-'s and 7-'s about something.

6-MeO-MIPT was made from the corresponding indole, by reaction with 2-nitroethyl acetate, the resulting 3-nitroethylindole catalytically hydrogenated to 6-MeO-T which was converted to the N-benzyloxycarbonyl derivative. This was reduced to 6-MeO-NMT which was in turn reductively coupled with acetone to provide 6-MeO-MIPT with a melting point of 89-91 °C and in an overall yield of 9%. MS (in m/z): C5H12N+ 86(100%); indolemethylene+ 160 (7%); parent ion 246 (4%). In human trials there was one report of some kind of neurological twinge at a 16 milligram level, but nothing else at trials of up to 50 milligrams and it has been shelved as being inactive.

The isomeric 7-MeO-MIPT was synthesized by the exact same five-step reaction sequence starting with 7-methoxyindole, in an overall yield of 24%. The actual reaction conditions for this conversion are detailed in the recipe for 4-MeO-MIPT. The mp of 7-MeO-MIPT was 72-73 °C and its MS (in m/z): C5H12N+ 86 (100%); indolemethylene+ 160 (5%); parent ion 246 (4%). Gas chromatographic analysis indicated that the product was only 80% pure, and three of the impurities were identified. One was 7-MeO-NIPT with MS (in m/z): C4H10N+ 72 (100%); indolemethylene+ 161/160 (13, 8%); parent ion 232 (4%). Another was 7-MeO-DMT with MS (in m/z): C3H8N+ 58 (100%); indolemethylene+ 160 (6%); parent ion 218 (9%). The third was 7-MeO-NMT with MS (in m/z): C2H6N+ 44 (100%); indolemethylene+ 161/160 (82, 39 %); parent ion 204 (5%). These three impurities represented approximately 5%, 3%, and 4%, resp., of the isolated product's final weight. It showed something going on at 20 mg orally with perhaps a little distortion in the visual field. And, separately, at 70 milligrams orally there might have been a light-headedness after a few minutes. Nothing more. It, too, has been given the kiss of death by being declared inactive at the 50 milligram level.

The last of the Mohicans, the tribe of compounds with the remarkably potent, orally active, N-methyl-N-isopropyl system on the tryptamine nitrogen atom, was the dimethoxy analogue with both the 5- and the 6-positions occupied with methoxy groups. This specific compound has its own recipe as it raises specific questions that deserve direct attention. The very close relative with the methylenedioxy group at this 5,6-location also has a separate recipe.

Two final laments. Remember that all these beautiful compounds are unique. Why do they behave the way they behave? I have no idea and there is never enough data to explain everything. I hate the fact that the word data is plural. But singular or plural keep collecting it (them), and keep trying to make sense of everything. And, a small point from my infancy. The Last of the Mohicans was one of the very first books I read, and I had very innocently accepted the footware of these Indians as being the metaphor for the people themselves. I had seen that title as having been, "The Last of the Moccasins." This is a pair of words that I still interchange without any defense, along with shoulder and soldier, avatar and atavar, and especially annoying when lecturing, irrelevant and irreverent. -shulgin; TIHKAL

The structural difference between 5-meo DIPT and 5-meo-MIPT being the substitutions to the amine nitrogen, one compound has two isopropyl groupings off the amine nitrogen, while the other has one methyl grouping and one isopropyl grouping off the amine nitrogen.

I have a good deal of experience with 5-meo-DIPT (though it was often combined with MDMA), but have only bioassayed 5-methoxy-N-methyl-N-isopropyl-tryptamine a handful of times. Honestly, I think these compounds are fairly similar experientialy, both carry a unique tactile component not common to tryptamine psychedelics, both are fairly fast acting, and both remind me a good deal of N,N-diethyl-tryptamine combined with a tactile component. They are definantly worth exploration...

-eg

 

[Yex]

I've been working with this substance from time to time lately.

On the note of music enhancement, something I've noticed with Moxy is that everything just seems louder. I can listen to music at a fraction of the volume that I normally do, and I feel like it is booming, completely enveloping me. This isn't unpleasant. Just thought that I'd add that.

I'd also like to add that this one seems like it can be really "superficial", or really productive, depending on set and setting and how far you choose to push it. I've done some pretty intense trancework on it, but I've also had experiences with it where I'm pretty content to sit around doing nothing at all.