Hi friends,
Some of you may remember that I planned on conjuring a NGF-promoting cocktail and combine that with microdoses of psilocybin in order to alleviate (or best-case scenario - cure) my lifelong stutter. The time of my relative financial stability came, so I'm starting the process with gathering as much information as I can before I devise one (or more) recipes that I'll test on myself. I need your help in relation to that. If there are any people in here that consider themselves well-versed in the field of neurobiology, I would very much appreciate your input.
So far I have come to the decision to include three main components in this cocktail, and those are as follows:
1. Lion's Mane (powdered, or extract) - I talked with a couple of people on a popular facebook mycology group and they told me that Paul Stamets' products are actually just re-labelled Mushroom Matrix products. If anyone knows more about this and if it's true at all, I'd appreciate your input!
2. Psilocybin microdoses (haven't settled on a dosing pattern yet, will look into it at a later stage)
3. DHEA (androstenolone) - there's sufficient evidence on the internet that this substance promotes NGF quite noticeably, binding to and activating some of the primary neurotrophin receptors, like TrkA, TrkC, and p75. However, I am aware that it also has an effect on the levels of testosterone, and is a negative allosteric modulator for the GABAa receptor, so I'm a bit on the line whether or not it's a good idea to include that in the mixture. I will discuss this with my doctor, but it would still be very helpful if anyone here has more knowledge and experience with this rather mainstream fitness supplement.
So far these are the substances I've largely decided on, but I would love to explore what else can be included in the mixture in a way that would synergize well with the others and maybe even potentiate their effects. I've also contacted the Institute of Reconstructive Neurobiology in Bonn, Germany, and am waiting for a reply on their end with any advice/knowledge on the topic.
That being said, I would really love it if you kind folk could share your opinion on the above, and maybe suggest more NGF-promoting substances that I can consider including in the cocktail.
I'm at a stage in my life where I'm sort of desperate for something to at least alleviate this issue. I recently started a new job as a software engineer, and anyone with experience in the field knows how many meetings per day there are, and how often we are expected to talk and explain stuff. It's getting really exhausting for me.
Thank you a lot in advance. Be well.
Some of you may remember that I planned on conjuring a NGF-promoting cocktail and combine that with microdoses of psilocybin in order to alleviate (or best-case scenario - cure) my lifelong stutter. The time of my relative financial stability came, so I'm starting the process with gathering as much information as I can before I devise one (or more) recipes that I'll test on myself. I need your help in relation to that. If there are any people in here that consider themselves well-versed in the field of neurobiology, I would very much appreciate your input.
So far I have come to the decision to include three main components in this cocktail, and those are as follows:
1. Lion's Mane (powdered, or extract) - I talked with a couple of people on a popular facebook mycology group and they told me that Paul Stamets' products are actually just re-labelled Mushroom Matrix products. If anyone knows more about this and if it's true at all, I'd appreciate your input!
2. Psilocybin microdoses (haven't settled on a dosing pattern yet, will look into it at a later stage)
3. DHEA (androstenolone) - there's sufficient evidence on the internet that this substance promotes NGF quite noticeably, binding to and activating some of the primary neurotrophin receptors, like TrkA, TrkC, and p75. However, I am aware that it also has an effect on the levels of testosterone, and is a negative allosteric modulator for the GABAa receptor, so I'm a bit on the line whether or not it's a good idea to include that in the mixture. I will discuss this with my doctor, but it would still be very helpful if anyone here has more knowledge and experience with this rather mainstream fitness supplement.
So far these are the substances I've largely decided on, but I would love to explore what else can be included in the mixture in a way that would synergize well with the others and maybe even potentiate their effects. I've also contacted the Institute of Reconstructive Neurobiology in Bonn, Germany, and am waiting for a reply on their end with any advice/knowledge on the topic.
That being said, I would really love it if you kind folk could share your opinion on the above, and maybe suggest more NGF-promoting substances that I can consider including in the cocktail.
I'm at a stage in my life where I'm sort of desperate for something to at least alleviate this issue. I recently started a new job as a software engineer, and anyone with experience in the field knows how many meetings per day there are, and how often we are expected to talk and explain stuff. It's getting really exhausting for me.
Thank you a lot in advance. Be well.
