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A new study published in Scientific Reports definitively observed that indolethylamine-N-methyltransferase (INMT) is found in both human and rat brains throughout the cerebral cortex, choroid plexus, and pineal gland. The importance of this finding is based on the fact that INMT is the enzyme responsible for biosynthesizing DMT from tryptamine. Prior studies were inconclusive regarding this based on out-dated protocols that lacked sensitivity.
The researchers found that in vivo extracellular levels of DMT in the cerebral cortex of normal behaving rats with or without the pineal gland were similar to those of serotonin. One of the most interesting (yet not surprising) findings of the study was that DMT levels increased significantly in the visual cortex of rats following induction of cardiac arrest. These increased levels of DMT in the visual cortex were independent of an intact pineal gland.
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q4lt.com
www.nature.com
The researchers found that in vivo extracellular levels of DMT in the cerebral cortex of normal behaving rats with or without the pineal gland were similar to those of serotonin. One of the most interesting (yet not surprising) findings of the study was that DMT levels increased significantly in the visual cortex of rats following induction of cardiac arrest. These increased levels of DMT in the visual cortex were independent of an intact pineal gland.
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New DMT Study Provides Additional Link to Gamma Wave Formation
Click here to access “New DMT Study Provides Additional Link to Gamma Wave Formation” found at it’s new home dmtquest.com. All past q4lt.com articles and future pieces can be found here at the blog section of dmtquest.com.
q4lt.com
Biosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DMT) in Mammalian Brain - Scientific Reports
N,N-dimethyltryptamine (DMT), a psychedelic compound identified endogenously in mammals, is biosynthesized by aromatic-L-amino acid decarboxylase (AADC) and indolethylamine-N-methyltransferase (INMT). Whether DMT is biosynthesized in the mammalian brain is unknown. We investigated brain...
www.nature.com