im sorry to hear that... its signs of a deeper problem though.. most people i turn on to mescal love it at 100mg range... although iv had people say they dont feel shit which just perplexed the hell out of me... what i have noticed though is the people that say they dont feel it usually are current or past heavy abusers of mdma as well as other things.. cross tolerance is quite possible..

as far as potentiation datura s. seeds really do the trick chew 3-4 and take say 200mg

or try drinking a strong cup of coffee 4 hours after you dose

and if it doesnt go well dont try again the next day wait at least a week

always keep in mind tolerance