I’m bringing all this up because nutmeg oil is so poorly understood. It’s a pretty decent psychedelic. It’s not this super toxic crap some people believe it is.

According to several sites I’ve seen, about 454 grams of marijuana orally is enough to reach a potential lethal dose of THC. That’s a lot. No one will ever eat that much. Now with nutmeg oil (not nutmeg powder or nute) which is way more concentrated than marijuana in terms of drug content, the potential lethal dose is about 196 grams (about 222 ml), some people say 100 ml (about 88 grams) or so. Think about that a little bit. Highly concentrated nutmeg oil is only 2.3-5.1 times more lethal than whole unconcentrated marijuana. That puts things into perspective I think.

Marijuana is one of the safest drugs known to mankind. Overdoses of it don't happen. The amount needed to overdose on it is huge, so it just doesn’t happen. Who's going to eat a pound of marijuana? No one in their right mind is going to do that. And it’s pretty much impossible to smoke a lethal dose of marijuana.

A person could easily drink 200 ml of nutmeg oil and die. So in that respect, it’s much more dangerous than marijuana. The maximum dose I’ve seen people use of nutmeg oil is 5 ml. The actually LD50 of nutmeg oil in man is unknown, but based on rats it should be 196 grams for a 75 kg (165 lb) adult.

To others reading this thread, please keep in mind that I’m talking about nutmeg oil and not whole/powder nutmeg. They are not the same. I can’t find LD50 information for whole/powder nutmeg. It contains toxins the oil doesn’t contain and produces side effects the oil doesn’t produce and is probably much more dangerous. For sure the trimyristin in whole nutmeg (not in the oil) is not healthy to ingest because it can cause fatty liver disease. I can’t find an LD50 for trimyristin though. Whole nutmeg contains a ton of trimyristin. And please don’t confuse myristicin with trimyristin, they are completely unrelated compounds.