3rdI - Yes! This is of use to me! Thank you for such a nice long answer
With regards to LSD, I am inclined to agree. Although my first important drug experience was with this molecule, I feel it is better for personal scrutiny, a change of perspective, 'cleaning the clocks' and recreation. I find it hard to imagine using it as my only or main sacrament for a number of reasons though.
With regards to DMT - I quickly came to a similar conclusion as you - that there is something divine about this stuff, and to use it in a recreational manner just isn't going to work. I do not understand how people can smoke DMT at concerts and festivals like it is 'just any old drug' - it is so much more than that to me, and part of me feels that these people are disrespecting the molecule and also retarding their spiritual development by using it as such. I have also found that since these feelings emerged I have become so much more reluctant to dish it out to anyone who wants (or thinks they want) the experience.
At first I was more than happy to share, but then when I realised certain people were just going to use it to "get fucked up" I started to only use it in private and with only a select few people. I am still happy to give the experience to those that I think approach this stuff with a respectful attitude. This is my place of worship and it has taken me a lot of time and effort to research and produce it - as well as a certain degree of personal risk, and I don't appreciate it being used in a callous manner - if people want DMT to get 'fucked up' then they can extract their own for all I care, DMT will put things in perspective for them over time no doubt...
I also don't want to irresponsibly give some to some one who thinks it is a recreational drug, only for them to have an experience that shatters their whole belief system. It would only create more negative hype about DMT and it would be my fault. If some one asks me for a hit of acid or 2CB on the other hand, yeah, sure 
I don't think you are sounding "holier than thou" by the way, I think it is the correct attitude to take - but I do think there is a very fine line between the correct attitude and a preachy, holier than thou attitude - so a degree of humility must be in the mix as well IMO. Maybe I came across as "holier than thou" in my response, IDK....
It's sad that your friend doesn't want to venture any deeper into DMT than the 'watching the trippyness of the room' stage, I'm sure they would soon realise that there is a good reason that people like to go as deep as they do - if you want sparkly visuals and a pleasant headspace, there are plenty of compounds that do just that, and for longer - without the risk of your entire reality being replaced, your ego crushed, and stern cosmic lessons being imposed on you. It is not a toy and I think your friend is taking the wrong drug to be blunt 
Best of luck with your Pharma mission - good vibes your way on that one!
Tele - I think a certain degree of analysis or reflection is unavoidable with these experiences, for me any way. But yes, I do agree that "rolling with the punches", "going with the flow" etc is the way to go with integrating these sorts of things. sometimes that takes a day, sometimes months or even longer. Having a hard experience can make one reluctant, but that IMO is part of the test that the molecule puts us through once in a while to see if we have the balls to carry on, you aren't going to grow if you spend your existence in a comfortable bubble after all...