Pharmacological Reference Desktop/Web Application

[Aetherius Rimor]

I'm starting the creation today of a software project to catalog as much pharmacological data on psychoactive substance.

I'm assuming there are only two current options as far as tool like this is concerned:

1. Expensive paid applications, usually in Java that I've seen due to Universities being the creators.
2. Open source website search lookups like Erowid/Wiki/Etc

If anyone can point me towards some similar software project as the idea I'm proposing, please let me know.

Mainly I'll be using this for my own personal reference and as current hobby. Design will be in the following:

ASP.NET WebService backend for interfacing with the live database.
C# .NET Desktop Application for viewing the data and sending queries to the server.
MSSQL backend database

That's the inital project setup, next major phase:

Web based version of application (In PHP due to my higher proficiency in it)
Mobile Device application (Android/iOS/etc, most likely done in a cross-platform development framework such as PhoneGap)

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Features:

Information kept on a drugs. Not just pharmaceutical, but also research/recreation drugs.

INN: Paracetamol
USAN: Acetaminophen
Classification: Sedative
Primary Usage: Antihistamine (Doxylamine Succinate would have sleep aid here)
Systematic (IUPAC) name: N-(4-hydroxyphenyl)ethanamide, N-(4-hydroxyphenyl)acetamide
Trade Names: Aminofen (USA), Anacin Aspirin Free (USA), Apra (USA), Feverall (USA), Genapap (USA), Tylenol (USA), Crocin (India)
Routes of Administration: Oral, rectal, intravenous
Oral Bioavailability: ~100%
Rectal Bioavailability: ??
Intravenous Bioavailability: 100%
Length of Action Oral: Xh XXm
Length of Action Rectal:
Length of Action IV:
Receptor Interaction:
- Name: Histamine H1 receptor Antagonist

Essentialy something similar to drugbank.ca but far more targetted emphasis on ease of use, especially in places where it might matter most (on the phone, having a User Friendly reference for on the spot decisions).

Information on drug interations that are known and suspected.

Dosage levels for MG/KG and MG/LB type information for dosage, and expected effects similar to erowid.

LD50 for every known susbtance, and a list of casulaties from the subject if known with links to more information on the causes.

Chemical structure

Chemical structure analysis to predict possible effects from unknown drugs

List of combinations of the drug that cause potentiation or other potentially dangerous side effects.

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I'm looking for any databases that are licensed for free non-commercial use at first for importing, and later on when this is closer to finished can start plugging in licensed databases for commercial distribution.

Commercial distribution would be based on a vastly more expanded data set accessibility that is updated yearly using a subscription revenue model.

Free version will have enough info required for Harm Prevention and be open source (only the database backend won't be)

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Any would be volunteers, opions or advice in this endeavor. New hobby side project.

 

[Aetherius Rimor]

Addendum:

I do know of sites like drugbank.ca, erwowid, and other forums that I can find information to research papers etc. I have a friend who will be ensuring we get data in a manner that won't violate copyright laws. I've been an entrepreneur for 8 years now, so the business logistics of this is not a concern, mainly the product.

Other sites similar to drugbank.ca or products used in the industry, if you know them, please let me know.

The document that gave me the inspiration for this: http://zakfallows.com/static/drugchart/drugchart.html

Receptor Actions would be from the DrugBank as well as research found as this to indicate affinity for the receptors:

Psychedelics and the Human Receptorome

We currently understand the mental effects of psychedelics to be caused by agonism or partial agonism of 5-HT2A (and possibly 5-HT2C) receptors, and we understand that psychedelic drugs, especially phenylalkylamines, are fairly selective for these two receptors. This manuscript is a reference...

www.plosone.org

 

[Adivino]

They probably don't list illicit drugs, but there are plenty of vademecums available. Doctors use them all the time. Check out, for example, epocrates.

 

[Aetherius Rimor]

I checked out Epocrates, but it seriously lacks in usability for the masses. First target audience will be non-knowledgable users to find out information for harm prevention. Later on get more indepth.

 

[Aetherius Rimor]

Main questions I need answered by this community would be following:

1. Is there any software out there that I can look at, that isn't just prescription (other than Epocrates)
2. Any ideas for feature suggestions.
3. Any recommendations for sources that have either a Non-commercial license (for development phase) and a Commercial license for production, or best, no copyright protections enforced?

Have a group of friends with similar interests who will be assisting me in this project, with various levels of expertise in related subject matters.

Will be regstering a Corp through my lawyer and setting up stock options for anyone of the people who initially contribute without monetary gain..

I will not be accepting help in any way online, personal/local friends only, but I will be posting updates and hopefully having some of the users here Beta Test it if it starts making good progress.