Hi all,
DMT is a molecule with reactive potential. Under certain conditions it can get modified to form other products with known or unknown activity. Two of the most common modifications people are aware of are:
1) its oxidation to DMT-N-Oxide, This process is triggered by the presence of oxidising agents, most notably atmospheric oxygen, in which case it oxidises in a fairly slow pace. Other oxidising agents like peroxide, potassium permanganate or potassium dichromate can oxidise it much faster. But whatever the way, the molecule changes. It is an yellow oil as a freebase, and it has slightly different activity than unoxidised DMT.
2) its deamination to indoleacetic acid (?). This is what the MAO system is most likely doing to DMT, creating a totally inactive compound.
But how about other possible reactivities of this molecule? Two possibilities are taken from TIHKAL, shown below:
1) cyclisation to a b-carboline. I am currently unaware under which conditions this would happen. I am also unaware of the activity of such a product.
2) N-demethylation to NMT or tryptamine. Again, I am unaware of any conditions that could make this happen or about the activity of NMT.
So, the question is: to what extent home extraction techniques provide the conditions for such derivation products to happen? Home extractors are aware of the fact that DMT will oxidise and take precautions to stop it, e.g. store it away from heat, light, air. But how about the other potential byproducts? Could for instance a very high or low pH or even FASA somehow affect the integrity of the DMT molecule? Could they cyclise it to a carboline? Or demethylate it to NMT or tryptamine? Can they brake it down to just indole or scatole?
DMT synthesis is prone to goofy by-products, such as NMT or tryptoline or whatever-may-you. Could the standard extraction techniques per se be able to modify the DMT molecule as they extract it in some way?
DMT is a molecule with reactive potential. Under certain conditions it can get modified to form other products with known or unknown activity. Two of the most common modifications people are aware of are:
1) its oxidation to DMT-N-Oxide, This process is triggered by the presence of oxidising agents, most notably atmospheric oxygen, in which case it oxidises in a fairly slow pace. Other oxidising agents like peroxide, potassium permanganate or potassium dichromate can oxidise it much faster. But whatever the way, the molecule changes. It is an yellow oil as a freebase, and it has slightly different activity than unoxidised DMT.
2) its deamination to indoleacetic acid (?). This is what the MAO system is most likely doing to DMT, creating a totally inactive compound.
But how about other possible reactivities of this molecule? Two possibilities are taken from TIHKAL, shown below:
1) cyclisation to a b-carboline. I am currently unaware under which conditions this would happen. I am also unaware of the activity of such a product.
2) N-demethylation to NMT or tryptamine. Again, I am unaware of any conditions that could make this happen or about the activity of NMT.
So, the question is: to what extent home extraction techniques provide the conditions for such derivation products to happen? Home extractors are aware of the fact that DMT will oxidise and take precautions to stop it, e.g. store it away from heat, light, air. But how about the other potential byproducts? Could for instance a very high or low pH or even FASA somehow affect the integrity of the DMT molecule? Could they cyclise it to a carboline? Or demethylate it to NMT or tryptamine? Can they brake it down to just indole or scatole?
DMT synthesis is prone to goofy by-products, such as NMT or tryptoline or whatever-may-you. Could the standard extraction techniques per se be able to modify the DMT molecule as they extract it in some way?
