My first successful rue extraction were on seeds that had been stored in my buddies closet for 5 years. My yield was low, but that's because my technique is awful with rue extractions. I made some changa and the extract is definitely active.
Harmalas are some of the most durable alkaloids around, afaik. The seeds should be fine to extract from and should be close to as potent, if not as potent as when you first got them
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