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Greetings ॐ. Indeed, salvia is fascinating, I'm truly captivated by her.

The starting solution used 48mg of green cold acetone extract powder and 500mg of HPBCD. I guessed 50% salvinorin above, but based on more experienced folks comments in this the sticky cold acetone thread, let's go with 33%. So there are 48x0.33= 16mg of salvinorin total. After drying and scraping there was "mountain" consisting of several different things: (1) complexed HPBCD-salvinorin (which would weigh 64mg because of the molar weights), (2) excess HPBCD (which would weigh 452mg since we started with 500mg), (3) 32mg of chlorophyll, and (4)
(hopefully but we don't know for sure) 0mg of uncomplexed salvinorin. They key here is that we have 16mg of salvinorin in the big pile. I divided the pile into 4 groups of 4mg salvinorin each weighing a total of 548/4 = 137mg.

Now for dosing. Erowid mentions that 1g of dried leaf yields 2.5mg of salvinorin. It also mentions that 2g of dried leaf quidding yields mild effects, which would be 5mg of salvinorin. Quidding is gentler and lasts longer than smoking so dosages are about 10x more for the same peak (!). Therefore I put the first pile (4mg of theoretically complexed salvinorin) under my tongue and waited. A solid light experience came on, well beyond placebo. Pleasant sensation of skin tightening/warming and slightly altered metal state.

After the light experience subsided plus two more hours, I took the other 3 piles (the rest). This would be 12mg of salvinorin, equivalent to 4.8g of dried leaf quidding. A moderate dose is considered 6g of dried leaf. I indeed felt moderate effects if not more (comparing to previous quidding experiences). This could be because the first salvia experience may not have been gone completely or because of some reverse tolerance after the first dose. I was laying in my bed feeling like I was sinking in it, aware of the pressure in my back, then oddly feeling that I was vertical and my bed was pushing me forward. This was followed by intense childhood memories. I've had similar experiences when quidding before. Overall I would say it was equivalent to quidding and that the salvinorin potency by weight where roughly the same with this way of administration. But more experimentation is needed to be sure and to confirm all these preliminary observations.

This is an interesting idea. Starting with chlorophyll free extract can also help understand this better and perform more precise experiments. For example, after complexation a non polar wash in a chemical that dissolves salvinorin but not HPBCD can be done. After decanting and drying the wash we could tell if all the salvinorin is complexed if we obtain no dry powder. We could lower the amount of excess HPBCD in the complexation procedure and check to see when free salvinorin starts to show up.

I'll carry your good wishes with me. My humble thanks.

<blockquote data-quote="Loveall" data-source="post: 3810602" data-attributes="member: 20">Greetings ॐ. Indeed, salvia is fascinating, I&#039;m truly captivated by her.The starting solution used 48mg of green cold acetone extract powder and 500mg of HPBCD. I guessed 50% salvinorin above, but based on more experienced folks comments in this the sticky cold acetone thread, let&#039;s go with 33%. So there are 48x0.33= 16mg of salvinorin total. After drying and scraping there was &quot;mountain&quot; consisting of several different things: (1) complexed HPBCD-salvinorin (which would weigh 64mg because of the molar weights), (2) excess HPBCD (which would weigh 452mg since we started with 500mg), (3) 32mg of chlorophyll, and (4)(hopefully but we don&#039;t know for sure) 0mg of uncomplexed salvinorin. They key here is that we have 16mg of salvinorin in the big pile. I divided the pile into 4 groups of 4mg salvinorin each weighing a total of 548/4 = 137mg. Now for dosing. <a href="https://erowid.org/plants/salvia/salvia_dose.shtml" target="_blank">Erowid</a> mentions that 1g of dried leaf yields 2.5mg of salvinorin. It also mentions that 2g of dried leaf quidding yields mild effects, which would be 5mg of salvinorin. Quidding is gentler and lasts longer than smoking so dosages are about 10x more for the same peak (!). Therefore I put the first pile (4mg of theoretically complexed salvinorin) under my tongue and waited. A solid light experience came on, well beyond placebo. Pleasant sensation of skin tightening/warming and slightly altered metal state.After the light experience subsided plus two more hours, I took the other 3 piles (the rest).&nbsp; This would be 12mg of salvinorin, equivalent to 4.8g of dried leaf quidding. A moderate dose is considered 6g of dried leaf. I indeed felt moderate effects if not more (comparing to previous quidding experiences). This could be because the first salvia experience may not have been gone completely or because of some reverse tolerance after the first dose. I was laying in my bed feeling like I was sinking in it, aware of the pressure in my back, then oddly feeling that I was vertical and my bed was pushing me forward. This was followed by intense childhood memories. I&#039;ve had similar experiences when quidding before. Overall I would say it was equivalent to quidding and that the salvinorin potency by weight where roughly the same with this way of administration. But more experimentation is needed to be sure and to confirm all these preliminary observations.This is an interesting idea. Starting with chlorophyll free extract can also help understand this better and perform more precise experiments. For example, after complexation a non polar wash in a chemical that dissolves salvinorin but not HPBCD can be done. After decanting and drying the wash we could tell if all the salvinorin is complexed if we obtain no dry powder. We could lower the amount of excess HPBCD in the complexation procedure and check to see when free salvinorin starts to show up.I&#039;ll carry your good wishes with me. My humble thanks.</blockquote>

[QUOTE="Loveall, post: 3810602, member: 20"] Greetings ॐ. Indeed, salvia is fascinating, I'm truly captivated by her. The starting solution used 48mg of green cold acetone extract powder and 500mg of HPBCD. I guessed 50% salvinorin above, but based on more experienced folks comments in this the sticky cold acetone thread, let's go with 33%. So there are 48x0.33= 16mg of salvinorin total. After drying and scraping there was "mountain" consisting of several different things: (1) complexed HPBCD-salvinorin (which would weigh 64mg because of the molar weights), (2) excess HPBCD (which would weigh 452mg since we started with 500mg), (3) 32mg of chlorophyll, and (4) (hopefully but we don't know for sure) 0mg of uncomplexed salvinorin. They key here is that we have 16mg of salvinorin in the big pile. I divided the pile into 4 groups of 4mg salvinorin each weighing a total of 548/4 = 137mg. Now for dosing. [url=https://erowid.org/plants/salvia/salvia_dose.shtml]Erowid[/url] mentions that 1g of dried leaf yields 2.5mg of salvinorin. It also mentions that 2g of dried leaf quidding yields mild effects, which would be 5mg of salvinorin. Quidding is gentler and lasts longer than smoking so dosages are about 10x more for the same peak (!). Therefore I put the first pile (4mg of theoretically complexed salvinorin) under my tongue and waited. A solid light experience came on, well beyond placebo. Pleasant sensation of skin tightening/warming and slightly altered metal state. After the light experience subsided plus two more hours, I took the other 3 piles (the rest). This would be 12mg of salvinorin, equivalent to 4.8g of dried leaf quidding. A moderate dose is considered 6g of dried leaf. I indeed felt moderate effects if not more (comparing to previous quidding experiences). This could be because the first salvia experience may not have been gone completely or because of some reverse tolerance after the first dose. I was laying in my bed feeling like I was sinking in it, aware of the pressure in my back, then oddly feeling that I was vertical and my bed was pushing me forward. This was followed by intense childhood memories. I've had similar experiences when quidding before. Overall I would say it was equivalent to quidding and that the salvinorin potency by weight where roughly the same with this way of administration. But more experimentation is needed to be sure and to confirm all these preliminary observations. This is an interesting idea. Starting with chlorophyll free extract can also help understand this better and perform more precise experiments. For example, after complexation a non polar wash in a chemical that dissolves salvinorin but not HPBCD can be done. After decanting and drying the wash we could tell if all the salvinorin is complexed if we obtain no dry powder. We could lower the amount of excess HPBCD in the complexation procedure and check to see when free salvinorin starts to show up. I'll carry your good wishes with me. My humble thanks. [/QUOTE]