derailing a bit re heart rate - get your body to a 'basal metabolic rate' and make there be a big gulp of oxygen circulating in your body before going for the hyperspace bus. Like those whales do before they go hunting giant squid... Heart rate is affected by the lowered % oxygen in the lungs and blood, and that is bound to happen as you super-slowly inhale that one big hit, for 30 seconds. By 35 seconds you've effectively held your breath for that long, and have inhaled less O2 than usual, so the brain (sympathetic nervous system) tells the heart to speed up and pump more blood. Try measuring heart rate after just holding your breath for 15, 30 45 ... sec... For me staying calm is possible, but it's hard to override the butterflys in the stomach feeling, keeping heart rate really low. Just breath deep for 5 - 10 minutes and fill your body with oxygen, and the heart will slow down. I always do 'the whale' and try to get my body hyper-relaxed and totally oxygenated before inhaling dmt. After 5 minutes of just lying or sitting, I get to a lowest- possible heart rate feeling my pulse, and then I start the engines ... But imagine this experiment - excercise then take a hit .>!?... you run up a steep hill to increase your heart rate to near 80% of maximum. At the top of the hill you previously setup a spot with a loaded bong and 30 mg dmt - a safe place. So when you get there you almost immediately take the full toke... imagine what it would be like to inhale that 30 mg with a racing heart...? After running hard with your heart racing, I bet the dmt would be transported to your brain via the blood in a denser 'wave', that could potentially change the experience... Maybe overwhelming the MAO enzymes there, quicker, so you'd be getting a "White Light" experience, like sometimes happens on dmt..? But what does excercise do to MAO enzymes..? Would more or less MAOs be hanging around in your body after a jog..? ... ok .. but to get back on topic - I have not tried salvia although I have posessed some X10 for over a year, waiting for my courage to well up. I bought a torch-lighter and dedicated pipe just to be ready, but I'm procrastinating... !~ Why do people say it makes you go "sideways" or 'flat' .?!