yeah, in 'sub-entheogenic' doses, Salvia divinorum can be chewed fairly regularly as a depression medication, without un-desirable side-effects..

but also, regardless of duration, slightly larger doses (chewed, as traditional, or smoked), following the experience seem to have a longer lasting 're-set' effect on people with long term depression's systems, and seem to regulate mood..

i've seen mood regulation also in animals, namely a billy goat who got off his lead and ate a salvia plant...went from headbutting nuisance to calm and responsive to behaviour requests