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Sleep rituals?

SympatheticMoron

Rising Star
I like puffing down ~5mg 1:1 harmine:dmt in a nice 10% herbal blend consisting of mullein, damiana, mint, sage. So about 50mg of that. Put that over a blue lotus base layer. Crank 'er down, shut the light "good night, love" and off I go. I'll instantly transition to sleep during the initial mild effects. Waking up in the morning and I'll get right after the days activities in a superior state of mind.

I don't have a need for a sleep aid typically but I found the effect to be quite enjoyable straight into a dreamstate that continues the night. In bed, I'm fully into 'there is nowhere to go, nothing to do' type of mind frame that allows them to work their best.

Anyone else have a bedtime ritual?
 
I have had it in me to continue to potentiate with the maoi administration as well.. during the initial meditation to the sleep state I'm quite aware that I took a substance that is making me feel good.
 
50-70mg of melatonin
Don't take this the wrong way, but that's quite a concerning amount of melatonin to supplement every evening.

The amount of melatonin an adult human body naturally produces is ~30μg. The average dosage you and dreamer take is about 2000 times higher than that. Additionally, supplementing melatonin in the form of OTC pills carries an enormous risk outlined in this study - Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin Content - which found an unpredictable divergence between the advertised and actual amount of melatonin present in 30 commercial supplements, and that range varied between 83% less and 478% more than advertised. If the latter applies to your particular supplement, this means you could be taking nearly 10,000 times more melatonin than your body naturally produces.

There is some data that links serious health conditions with supplementing too much melatonin. Hypermelatoninemia is a very real thing and it can cause conditions like hypogonadotropic hypogonadism, polycystic ovarian syndrome (PCOS), and Rabson-Mendenhall syndrome (which leads to diabetes and enlargement of the pineal gland).

I'm not trying to be nosy and interject where my opinion has not been asked for, but I'm just pointing this out because I care for you two's health. Based on what the linked study exposes, I generally stopped taking melatonin supplements entirely and instead replaced them with 500mg L-Tryptophan 30-60 min before sleep. It's a precursor to melatonin, and there's less variability in the advertised and actual amounts of it in the supplements I buy. I also take some magnesium L-Threonate.

Generally speaking, unless I do some activity that excites and overstimulates my mind before bed, and I try not to have a blue-light (or any bright light at all) emitter blasting my face for the last 2-3-4 hours of my day, I sleep like a baby.

If bright lights are not something you can easily avoid in the evening, there are some products on the market developed specifically for reducing the impact of those lights on your sleep, such as the recently released Roka collaboration with Andrew Huberman - Wind Down™ by ROKA & Dr. Andrew Huberman

One additional interesting mention regarding lights is that light sources which are located above you (on the ceiling) excite the brain significantly more than those located on the same level (or lower) of your eyes. The reason for this is evolutionary and has to do with the circadian rythm of our predecessors, which evolved to acutely react to light coming from above (i.e. sunrise, and the respective start of the new day) by spiking your levels of cortisol, thus making it significantly harder to fall and stay asleep. It does so because it needs you to be focused and prepared to deal with hunting and securing the nourishment needs of your tribe. All that is to say, if you can, you should turn off overhead lights in the evening.

Cheers!
 
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I'd love to check on some studies that shed more light on this, as I love melatonin, when I haven't taken it for a while I get the most vivid and incredible dreams on it.

What I was referring to isn't something you necessarily will be able to perceive or notice in terms of side effects until it's far too late to undo the damage. I'm sure there are many combinations that make it work even better, but my point was that the dose makes the poison.
 
I'd love to check on some studies that shed more light on this, as I love melatonin, when I haven't taken it for a while I get the most vivid and incredible dreams on it.

What I was referring to isn't something you necessarily will be able to perceive or notice in terms of side effects until it's far too late to undo the damage. I'm sure there are many combinations that make it work even better, but my point was that the dose makes the poison.
Maybe my brain responded by producing less seratonin? I experienced this multiple times with prolonged use and don't have any issues when combined w a bit of harmalas.
 
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Indeed, over the counter melatonin supplements are all over the place, this has been a big issue for a long time and applies to supplements across the board outside just melatonin. It's very important to ensure you are getting a quality product from a reputable manufacturer. We use pure powder of known quality and dosage for our experiments.

If you have more data linking melatonin to negative health outcomes, I'd love to review it. I've collected quite a few articles over the year in the research thread with a particular emphasis on long-term use and high dosages and it's always reported as well tolerated with minimal side effects.

Lemoine, Patrick, et al. "Prolonged-release melatonin for insomnia–an open-label long-term study of efficacy, safety, and withdrawal." Therapeutics and clinical risk management 7 (2011): 301 - 2mg over the course of 6-12 months was well tolerated and no withdrawal effects or suppression of endogenous production was noted.

der HEIJDEN, KRISTIAAN B. VAN, et al. "Effect of melatonin on sleep, behavior, and cognition in ADHD and chronic sleep-onset insomnia." Journal of the American Academy of Child & Adolescent Psychiatry 46.2 (2007): 233-241 - Doses of 3-6 mg were well tolerated.

Sack RL, Lewy AJ, Blood ML, Stevenson J, Keith LD. Melatonin administration to blind people: phase advances and entrainment. J Biol Rhythms. 1991;6(3):249-61 - Doses of 5-7 mg were well tolerated

Cardinali, Daniel P., et al. "Therapeutic application of melatonin in mild cognitive impairment." American journal of neurodegenerative disease 1.3 (2012): 280 - Doses of 3-9 mg administered for 3 years were well tolerated.
*This is one is particularly juicy with references to multiple higher dose and longer term studies. I'd like to point out this section in particular:
Indeed, melatonin has a high safety profile; it is usually remarkably well tolerated, and in some studies, it has been administered to patients at very large doses. Melatonin (300 mg/day) for up to 3 years decreased oxidative stress in patients with amyotrophic lateral sclerosis [59]. In children with muscular dystrophy, 70 mg/day of melatonin reduced cytokines and lipid peroxidation [60]. Doses of 80 mg melatonin hourly for 4 hours were given to healthy men with no undesirable effects other than drowsiness [61]. In healthy women given 300 mg melatonin/day for 4 months, there were no side effects [62]. A recent randomized controlled double-blind clinical trial on 50 patients referred for liver surgery indicated that a single preoperative enteral dose of 50 mg/kg melatonin (i.e., an equivalent to 3 g for a 60-kg adult) was safe and well tolerated [63].
 
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Indeed, over the counter melatonin supplements are all over the place, this has been a big issue for a long time and applies to supplements across the board outside just melatonin. It's very important to ensure you are getting a quality product from a reputable manufacturer. We use pure powder of known quality and dosage for our experiments.

If you have more data linking melatonin to negative health outcomes, I'd love to review it. I've collected quite a few articles over the year in the research thread with a particular emphasis on long-term use and high dosages and it's always reported as well tolerated with minimal side effects.

Lemoine, Patrick, et al. "Prolonged-release melatonin for insomnia–an open-label long-term study of efficacy, safety, and withdrawal." Therapeutics and clinical risk management 7 (2011): 301 - 2mg over the course of 6-12 months was well tolerated and no withdrawal effects or suppression of endogenous production was noted.

der HEIJDEN, KRISTIAAN B. VAN, et al. "Effect of melatonin on sleep, behavior, and cognition in ADHD and chronic sleep-onset insomnia." Journal of the American Academy of Child & Adolescent Psychiatry 46.2 (2007): 233-241 - Doses of 3-6 mg were well tolerated.

Sack RL, Lewy AJ, Blood ML, Stevenson J, Keith LD. Melatonin administration to blind people: phase advances and entrainment. J Biol Rhythms. 1991;6(3):249-61 - Doses of 5-7 mg were well tolerated

Cardinali, Daniel P., et al. "Therapeutic application of melatonin in mild cognitive impairment." American journal of neurodegenerative disease 1.3 (2012): 280 - Doses of 3-9 mg administered for 3 years were well tolerated.
*This is one is particularly juicy with references to multiple higher dose and longer term studies. I'd like to point out this section in particular:
After reviewing what you have shared, as well as this study - Safety of higher doses of melatonin in adults: A systematic review and meta-analysis - it seems my concerns are mostly insubstantial, at least based on what we currently know. Melatonin does indeed seem relatively safe in higher doses, so please accept my apologies for making it seem otherwise.

I suppose the primary driver for that was the very small amount of it we naturally produce compared to the enormous amounts that people supplement with. I know this is not a scientific approach, but I always keep an eye out on supplementation that goes so far beyond the natural production of the hormone in question. And I suppose this applies to a lot of aspects - if you take thousands of times more vitamin D, for example, than what your skin naturally produces, and what you consume with foods, you'll most likely experience adverse effects, but melatonin seems to have quite a stable safety profile.

Thank you for educating me. Much appreciated. <3
 
i use to make my usual scanner zen meditation and with an incense goes pretty well = )

i used to smoke marijuana before sleep but.. But / after starting psychoanalysis therapy I realized that the habit was making some interference in the flow-becoming of inconcience world and all, so I left it.
and now I dream better
 
i used to smoke marijuana before sleep but.. But / after starting psychoanalysis therapy I realized that the habit was making some interference in the flow-becoming of inconcience world and all, so I left it.
and now I dream better
There's also a fair bit of research that shows THC disrupts the architecture of your sleep, especially the REM phase, which would explain why you dream better after stopping.
 
There's also a fair bit of research that shows THC disrupts the architecture of your sleep, especially the REM phase, which would explain why you dream better after stopping.
yea... maybe? there is probably some research on brain area reactions and activity and so on. Interesting inferences about that attemp to explain, but of course. However, seen from limited artifacts and from outside the real eye.
I tend to be skeptical about the conclusions they have to offer sometimes. maybe because... I guess they can't deal with the dream ontology of the phenomenon in some way? but yea... anyways, I don't think anything is more enriching for one's own spiritual path than subjective interpretations of the phenomenon, especially when it comes to the world of dreams 🌠
 
There's also a fair bit of research that shows THC disrupts the architecture of your sleep, especially the REM phase, which would explain why you dream better after stopping.
and something to add is that this poetic appreciation is also one of the reasons why I love reading things from this forum, like the trip reports... they are such personal experiences that touch my literary vein ♥️
 
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