Hey JM.  Absolutely.  People have life transforming moments on psychedelics all the time.  There is a reason why MAPS and other research institutions are pushing so hard to reintegrate LSD, Psilocybin, Iboga, etc... into common medical practice again.  These substances, under the right set and setting, can be used for profound life changing experiences. 

Every valid academic study with psychedelics has concluded that no harm was seen, either short term or long term, and that the overall impact on the individual was extremely positive.  In fact, speaking of health... I just cracked open Albert Hoffan's book, "LSD: My Problem Child." to discover that he lived an extraordinarily healthy life to the age of 102!!!  102!!!  And this is a guy that has most likely taken more LSD than all of the nexus combined!

I urge you to just google: research "Fill in Drug Name Here"

I could go on endlessly about the current application happening right now.  Ecstacy used for PTSD for US war veterans, psilocybin used for end of life anxiety, cannabis to treat depression, stopping heroid & cocain addition practically overnight with Iboga, Ayahuasca (DMT) being deemed beneficial for society in South America...  The list keeps growing. 

If you have failed to turn a negative point of your life around with the use of psychedelics... then I would strongly consider finding someone who you trust to help "guide" you... and good luck!

~Jez