A recent intense Ayahuasca journey has lead me to investigating further the alkaloid content of my home grown materials.

Extraction of dried Psychotria viridis leaf has shown to average around 1% DMT when grown in optimal conditions, stressed and harvested at dusk to ensure maximum alkaloid yield.  A method closely following steps outlined within the lextek was used to obtain the alkaloid.

The ‘Pictoral guide to caapi vine alkaloid extraction’ was used to extract vine alkaloids from home grown Banisteriopsis caapi ‘Cielo’.  Stressed vine was harvested and a fairly even range of vine was selected from sections including the vine base, main stem and smaller finger width stems.  Final extract yielded 0.67% caapi freebase alkaloids.

My recent experience leading to total dissolution self was the result of a brew containing 22g of dried Psychotria viridis leaf (approximately 220mg DMT) and 100g of dried vine (approximately 670mg of caapi alkaloids) per dose.

The study paper ‘Seeing with the eyes shut: Neural basis of Enhanced imagery following Ayahuasca Ingestion’ by Draulio et.al 2012 (see attached), has recently come to my attention and the dosage information I found to be of interest.  It is as follows –

Each patient had 2.2ml/kg of Ayahuasca containing 0.8 mg/mL of DMT and 0.21 mg/mL of harmine.

My weight = 85kg

85kg x 2.2mL = 187mLs

DMT: 187mL x 0.8mgs = 149.6mg

harmine: 187mL x 0.21mg = 39.27mg

Assuming this is correct, the harmine seems very low to me.

I have worked out that to make a similar brew using my materials I would need to brew the following materials per dose –

15g of dried Psychotria viridis leaf = 150mg DMT

5.9g of dried caapi vine = 39.53mg of caapi alkaloids.

I am yet to try this brew but it was obviously affective at causing the Ayahuasca state within the study.

What opinion do folks have on this brew?  Should it adequately produce the Ayahuasca experience or is there something wrong in either my working out or the dosage info within the study paper?