Cheers to Casey. What a response

I would add my hat to the "there is a definite subjective difference in experience between batches/crystal varieties" camp. Whether this is due to difference in purity and how a higher purity hits/is absorbed by receptors, "inactive" isomers interacting with active isomers and becoming active in some way through an entourage effect, or simply the care and love with which the product has been created and handled (vibes/degradation/whatever) I make no claim to know. I can assure you though- needlepoint, white white family fluff, and eggshell all elicit a different experience and can be picked out of a lineup. To be fair, the needlepoint and white white fluff could be mistaken for one another, but when you have a lesser product such as eggshell- you know.

My theory is that although other isomers may appear "inactive" they can still bind to receptors, blocking the good good from getting where it needs to get to do the wheeeee thing and make your brain go brrrrrrrrrr. Thus a more purified and refined product makes brain go brrrrrrr more better.

Feel free to quote me for your academic journal.