Nobody ever takes LSD in milligrams.

LSD does not "cut off" your brains serotonin supply.

(I'm not sure where a claim like that could even originate...it's possible that someone was referring to "dorsal raphe nuclei" which are firing serotonin while you are awake, the firing rate slows as you tire, and stops entirely in deep sleep, when you take psychedelic compounds your dorsal raphe nuclei stop firing even though you are fully awake, so it's possible that this concept was simply misunderstood by someone who thought this meant serotonin was being "cut off" )

The pharmocological properties of LSD are complex, and are not fully understood, [MEDIA=youtube]rG94kxT9ZFE[/MEDIA] here David E. Nichols elucidated the chemistry and pharmocological properties of LSD and related compounds, the lecture is in classroom format, and it is basic enough to be understood by most, I highly recommend this lecture as well as this lecture [MEDIA=youtube]ZJtdZUy1LYE[/MEDIA] if you are seeking to understand how these compounds are affecting the brain and neurochemistry...Dr Robin Carhart-Harris and Dr. David nutt also.did some amazing work with fMRI scanning and psychedelics...

Here is a quick outline of the pharmocological properties of LSD:

There's a good deal of misinformation and disinformation out there regarding these compounds, however if you stick to reliable information sources such as Albert Hoffman, Alexander shulgin, David E. Nichols, www.maps.org , Heffter Research Institute | Advancing Psilocybin Research , www.erowid.org , and so on, there are many reliable chemists, researchers, and organizations which can provide you with accurate and up to date information...

And my first recommendation for any person interested in psychedelics is to seek out accurate information and research/study.

-eg