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Still seems somewhat wasteful, as both have nearly the same solubility . So you need to overshoot with Ethanol to keep all the Harmine in solution. Therefore of course only working with excess mixtures of THH:Harmin.

But of course people could just evaporate that residual EtOH and just get

1x Mix with less Harmine
+
1x Mix with more Harmine

And not loose anything.

Also is there any information if THH is also metabolized by MAO-A/B? That constrained structure already looks suspicius of causing some different enzyme interactions, but as it is also not a MAOI itself, does it even have any interaction with those MAOs ?

Guess in any case leaving that Harmine inside will not make problems, just will always be slight yellow.

That still sounds pretty epic. So I was checking if any less-material administration might be worth a try and tried the vapor method.

50 mg THH were vaporized within ~ 10 min.

Divided that whole powder into 4x portions of ~ 12 mg.

Effect:

none ...

Sadly did not feel any real effect compared to that eaten 420 mg which was definetly very dreamy.

But have to say that even if I tried holding that vapor for at least 15 sec, there was always a HUGE cloud coming out of my mouth when exhaling. So seems like lung absorption is really poor ... probably therefore minimal efficiency when smoked. Such a pity, as it is vaporizing quite nicely.

At least my banger lid looked quite funny after vaping Quite a bunch of material stuck there, but could not vape it faster due to holding breath even longer than 'normal'. Picture attached.

PS: Of course I made the mistake again :thumb_dow :thumb_dow At 3. and 4. it's of course HARMIN and not HARMALIN. omg will never learn it :?

<blockquote data-quote="Brennendes Wasser" data-source="post: 3903095" data-attributes="member: 36938">Still seems somewhat wasteful, as both have nearly the same solubility <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite10" alt=":oops:" title="Oops!&nbsp; &nbsp; :oops:" loading="lazy" data-shortname=":oops:" /> . So you need to overshoot with Ethanol to keep all the Harmine in solution. Therefore of course only working with excess mixtures of THH:Harmin.But of course people could just evaporate that residual EtOH and just get 1x Mix with less Harmine+1x Mix with more HarmineAnd not loose anything.Also is there any information if THH is also metabolized by MAO-A/B? That constrained structure already looks suspicius of causing some different enzyme interactions, but as it is also not a MAOI itself, does it even have any interaction with those MAOs ?Guess in any case leaving that Harmine inside will not make problems, just will always be slight yellow.That still sounds pretty epic. So I was checking if any less-material administration might be worth a try and tried the vapor method. 50 mg THH were vaporized within ~ 10 min. Divided that whole powder into 4x portions of ~ 12 mg. Effect:none ...Sadly did not feel any real effect compared to that eaten 420 mg which was definetly very dreamy. But have to say that even if I tried holding that vapor for at least 15 sec, there was always a HUGE cloud coming out of my mouth when exhaling. So seems like lung absorption is really poor ... probably therefore minimal efficiency when smoked. Such a pity, as it is vaporizing quite nicely.At least my banger lid looked quite funny after vaping <img class="smilie smilie--emoji" loading="lazy" alt="😁" title="Beaming face with smiling eyes&nbsp; &nbsp; :grin:" src="/styles/default/xenforo/smilies/nexus/unicode/64/1f601.png" data-shortname=":grin:" /> Quite a bunch of material stuck there, but could not vape it faster due to holding breath even longer than &#039;normal&#039;. Picture attached.PS: Of course I made the mistake again :thumb_dow :thumb_dow <img class="smilie smilie--emoji" loading="lazy" alt="😁" title="Beaming face with smiling eyes&nbsp; &nbsp; :grin:" src="/styles/default/xenforo/smilies/nexus/unicode/64/1f601.png" data-shortname=":grin:" /> At 3. and 4. it&#039;s of course HARMIN and not HARMALIN. omg will never learn it :?</blockquote>

[QUOTE="Brennendes Wasser, post: 3903095, member: 36938"] Still seems somewhat wasteful, as both have nearly the same solubility :oops: . So you need to overshoot with Ethanol to keep all the Harmine in solution. Therefore of course only working with excess mixtures of THH:Harmin. But of course people could just evaporate that residual EtOH and just get 1x Mix with less Harmine + 1x Mix with more Harmine And not loose anything. Also is there any information if THH is also metabolized by MAO-A/B? That constrained structure already looks suspicius of causing some different enzyme interactions, but as it is also not a MAOI itself, does it even have any interaction with those MAOs ? Guess in any case leaving that Harmine inside will not make problems, just will always be slight yellow. That still sounds pretty epic. So I was checking if any less-material administration might be worth a try and tried the vapor method. 50 mg THH were vaporized within ~ 10 min. Divided that whole powder into 4x portions of ~ 12 mg. Effect: none ... Sadly did not feel any real effect compared to that eaten 420 mg which was definetly very dreamy. But have to say that even if I tried holding that vapor for at least 15 sec, there was always a HUGE cloud coming out of my mouth when exhaling. So seems like lung absorption is really poor ... probably therefore minimal efficiency when smoked. Such a pity, as it is vaporizing quite nicely. At least my banger lid looked quite funny after vaping 😁 Quite a bunch of material stuck there, but could not vape it faster due to holding breath even longer than 'normal'. Picture attached. PS: Of course I made the mistake again :thumb_dow :thumb_dow 😁 At 3. and 4. it's of course [b]HARMIN [/b]and not [b]HARMALIN[/b]. omg will never learn it :? [/QUOTE]