Hmm that's interesting. Definitely makes sense. I swear the emotional/stress aspects of this illness are worse than the physical. The neuropathy and joint pain don't bother me nearly as much as the fear of spontaneously stroking out or having a heart attack. I just feel so fragile these days which has been my main concern with going deep on it. I have tripped since having Lyme but mostly on synthetics or mushrooms. Nothing with MAOI or quite as violently purgative. They've all gone well and are probably the strongest anti inflammatories i've yet to come across. But the nerves leading up to it... geez. I had a recent opportunity to do Ayahuasca and bailed out because of it only to regret it. It was my wifes first time in ceremony and i missed it  Definitely comforting to know another Lyme patient has been through it with success. My other concern was interactions with the herbs i was taking, but i was assured that antidepressants and stimulants are the only real concern

I'll keep that in mind if i ever prepare my own brew. Unfortunately i don't have much control over the preparation because i prefer to take in ceremony with a guide i've come to know and love. I know this isn't most peoples preference, but i honestly couldn't imagine doing it any other way. The communion, group prayer and healing is where i find all the benefit. Otherwise it's just another overly nauseating and incapacitating psychedelic to me. Not to denounce it's medicinal value, it's just not my preferred road for traveling solo.

I gotta say though it's a little depressing hearing you've been through this for 8 years. I've only been treating 3-4 months and doing pretty well but sometimes i fear I'm plateauing and will never get healed. Would love to hear what you've tried